Genomic distribution of 5-Hydroxymethylcytosine in mouse kidney and its relationship with gene expression

Ten-Eleven Translocation (TET) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytonsie (5hmC). Our recent work found a decline in global 5hmC level in mouse kidney insulted by ischemia reperfusion (IR). However, the genomic distribution of 5hmC in mouse kidney and its relationship with ge...

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Veröffentlicht in:	Renal failure 2016-07, Vol.38 (6), p.982-988
Hauptverfasser:	Wang, Hao, Huang, Ning, Liu, Yuqi, Cang, Jing, Xue, Zhanggang
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Methylcytosine - analogs & derivatives 5-Methylcytosine - metabolism 5hmC Acute Kidney Injury - genetics Animals DNA Methylation Epigenesis, Genetic Gene Expression ischemia reperfusion Kidney - metabolism Male Mice Mice, Inbred C57BL mouse kidney Reperfusion Injury - genetics
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