Interferon gamma modulates sensitivity of CML cells to tyrosine kinase inhibitors

Immune effector cells such as T and NK cells can efficiently eliminate tumor cells. However, when activating oncogenic signaling pathways or protective mechanisms against cell death are active, immune cells can also confer therapy resistance. Here, we analyzed the role of activated T and NK cells an...

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Veröffentlicht in:	Oncoimmunology 2016-01, Vol.5 (1), p.e1065368-e1065368
Hauptverfasser:	Held, Stefanie Andrea Erika, Heine, Annkristin, Kesper, Anne Ruth, Schönberg, Kathrin, Beckers, Anika, Wolf, Dominik, Brossart, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic myelogenous leukemia immunotherapeutic interferon gamma Original Research resistance tyrosine kinase inhibitors
Online-Zugang:	Volltext
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