Multifunctionalized iron oxide nanoparticles for selective drug delivery to CD44-positive cancer cells

Nanomedicine nowadays offers novel solutions in cancer therapy and diagnosis by introducing multimodal treatments and imaging tools in one single formulation. Nanoparticles acting as nanocarriers change the solubility, biodistribution and efficiency of therapeutic molecules, reducing their side effe...

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Veröffentlicht in:	Nanotechnology 2016-02, Vol.27 (6), p.065103-65112
Hauptverfasser:	Aires, Antonio, Ocampo, Sandra M, Simões, Bruno M, Josefa Rodríguez, María, Cadenas, Jael F, Couleaud, Pierre, Spence, Katherine, Latorre, Alfonso, Miranda, Rodolfo, Somoza, Álvaro, Clarke, Robert B, Carrascosa, José L, Cortajarena, Aitziber L
Format:	Artikel
Sprache:	eng
Schlagworte:	active targeting Biotechnology Cancer Cell Line, Tumor Chemistry, Pharmaceutical - methods Circulating controlled drug release Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Deoxycytidine - chemistry Drug Carriers - administration & dosage Drug Carriers - chemistry Drug delivery systems Drug Delivery Systems - methods Ferric Compounds - administration & dosage Ferric Compounds - chemistry Humans Hyaluronan Receptors - metabolism Iron oxides magnetic nanoparticles Magnetics - methods multifunctionalization nanocarriers nanomedicine Nanomedicine - methods Nanoparticles Nanoparticles - administration & dosage Nanoparticles - chemistry Nanostructure Neoplastic Cells, Circulating - metabolism Neoplastic Stem Cells - metabolism Therapy Tissue Distribution - physiology
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