Intravitreal Aflibercept for Treatment-Resistant Neovascular Age-Related Macular Degeneration: 12-Month Safety and Efficacy Outcomes

Purpose: To prospectively assess the safety and efficacy of intravitreal aflibercept for treatment-resistant neovascular age-related macular degeneration (nAMD). Methods: This prospective, non-randomized clinical trial included 49 patients with treatment-resistant nAMD who received 2 mg intravitreal...

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Veröffentlicht in:	Ophthalmic research 2016-01, Vol.55 (2), p.84-90
Hauptverfasser:	Chang, Andrew A., Broadhead, Geoffrey K., Hong, Thomas, Joachim, Nichole, Syed, Adil, Schlub, Timothy E., Toth, Levente, Peto, Tunde, Zhu, Meidong
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Angiogenesis Inhibitors - adverse effects Angiogenesis Inhibitors - therapeutic use Choroidal Neovascularization - diagnosis Choroidal Neovascularization - drug therapy Female Fluorescein Angiography Humans Intravitreal Injections Male Original Paper Prospective Studies Receptors, Vascular Endothelial Growth Factor - adverse effects Receptors, Vascular Endothelial Growth Factor - therapeutic use Recombinant Fusion Proteins - adverse effects Recombinant Fusion Proteins - therapeutic use Tomography, Optical Coherence Treatment Outcome Vascular Endothelial Growth Factor A - antagonists & inhibitors Visual Acuity - physiology Wet Macular Degeneration - diagnosis Wet Macular Degeneration - drug therapy
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