The interaction between plant lectins and the small intestinal epithelium: A primary cause of intestinal disturbance
The literature concerning the effects of plant lectins on the small intestinal epithelium is reviewed. It appears that after oral intake, intact plant lectins can reach the small intestinal lumen. Their binding to the mucosal surface evokes an increased synthesis of glycoproteins and a degeneration...
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| Veröffentlicht in: | The Veterinary quarterly 1989-04, Vol.11 (2), p.108-115 |
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| container_end_page | 115 |
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| container_issue | 2 |
| container_start_page | 108 |
| container_title | The Veterinary quarterly |
| container_volume | 11 |
| creator | Kik, M. J. L. Rojer, J. M. Mouwen, J. M. V. M. Koninkx, J. F. J. G. van Dijk, J. E. van der Hage, M. H. |
| description | The literature concerning the effects of plant lectins on the small intestinal epithelium is reviewed. It appears that after oral intake, intact plant lectins can reach the small intestinal lumen. Their binding to the mucosal surface evokes an increased synthesis of glycoproteins and a degeneration of the intestinal epithelium. The epithelial alterations may result in hyperregenerative villus atrophy and endogenous nitrogen loss. These changes ultimately can lead to less efficient feed conversion, diminished growth, scouring, wasting and death. The possible significance of plant lectins in digestive disturbances in farm animals is suggested. |
| doi_str_mv | 10.1080/01652176.1989.9694207 |
| format | Article |
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The possible significance of plant lectins in digestive disturbances in farm animals is suggested.</description><identifier>ISSN: 0165-2176</identifier><identifier>EISSN: 1875-5941</identifier><identifier>DOI: 10.1080/01652176.1989.9694207</identifier><identifier>PMID: 2662569</identifier><language>eng</language><publisher>England: Taylor & Francis Group</publisher><subject>Animals ; Epithelium - drug effects ; Intestinal Diseases - etiology ; Intestinal Diseases - veterinary ; Intestine, Small - drug effects ; Lectins - pharmacology</subject><ispartof>The Veterinary quarterly, 1989-04, Vol.11 (2), p.108-115</ispartof><rights>Copyright Taylor & Francis Group, LLC 1989</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-2d88b149e7bfb3ec2183829c4e8b04b20314b5d5bf0f00d03c84b14b19dbedfa3</citedby><cites>FETCH-LOGICAL-c408t-2d88b149e7bfb3ec2183829c4e8b04b20314b5d5bf0f00d03c84b14b19dbedfa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2662569$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kik, M. 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These changes ultimately can lead to less efficient feed conversion, diminished growth, scouring, wasting and death. The possible significance of plant lectins in digestive disturbances in farm animals is suggested.</description><subject>Animals</subject><subject>Epithelium - drug effects</subject><subject>Intestinal Diseases - etiology</subject><subject>Intestinal Diseases - veterinary</subject><subject>Intestine, Small - drug effects</subject><subject>Lectins - pharmacology</subject><issn>0165-2176</issn><issn>1875-5941</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1v1DAQhi0EKtuWn1DJJ27Z2o6d2JyoqtIiVeLSni1_jIWRkyy2o6r_Hi8bECdOlt55xjPzIHRFyZ4SSa4JHQSj47CnSqq9GhRnZHyDdlSOohOK07dod2S6I_QenZfygxBOBB_O0BkbBiYGtUP16TvgOFfIxtW4zNhCfQGY8SGZueIELZ0LNrPHtZFlMin95kvLTcJwiC1PcZ0-4Rt8yHEy-RU7sxbAS_iX9LHUNVszO7hE74JJBT5s7wV6_nL3dPvQPX67_3p789g5TmTtmJfSUq5gtMH24BiVvWTKcZCWcMtIT7kVXthAAiGe9E7yxluqvAUfTH-BPp7-PeTl59oW0VMsDlI7DZa16FERoXrCGihOoMtLKRmC3i7RlOijbf3Htj7a1pvt1ne1DVjtBP5v16a31T-f6nEOS57My5KT19W8piWH3FTEovv_j_gFTKaRRQ</recordid><startdate>198904</startdate><enddate>198904</enddate><creator>Kik, M. 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| identifier | ISSN: 0165-2176 |
| ispartof | The Veterinary quarterly, 1989-04, Vol.11 (2), p.108-115 |
| issn | 0165-2176 1875-5941 |
| language | eng |
| recordid | cdi_pubmed_primary_2662569 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Epithelium - drug effects Intestinal Diseases - etiology Intestinal Diseases - veterinary Intestine, Small - drug effects Lectins - pharmacology |
| title | The interaction between plant lectins and the small intestinal epithelium: A primary cause of intestinal disturbance |
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