Genetic and Morphological Features of Human iPSC-Derived Neurons with Chromosome 15q11.2 (BP1-BP2) Deletions

Background: Copy number variation on chromosome 15q11.2 (BP1-BP2) causes a deletion of CYFIP1, NIPA1, NIPA2 and TUBGCP5. Furthermore, it also affects brain structure and elevates the risk for several neurodevelopmental disorders that are associated with dendritic spine abnormalities. In rodents, alt...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Complex psychiatry 2015-07, Vol.1 (2), p.116-123
Hauptverfasser:	Das, Dhanjit K., Tapias, Victor, D''Aiuto, Leonardo, Chowdari, Kodavali V., Francis, Lily, Zhi, Yun, Ghosh, Ayantika, Surti, Urvashi, Tischfield, Jay, Sheldon, Michael, Moore, Jennifer C., Fish, Ken, Nimgaonkar, Vishwajit L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Preliminary Study
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!