Female mice with loss-of-function ITCH display an altered reproductive phenotype

Major progress in deciphering the role of the E3 ligase, ITCH, in animal physiology has come from the generation and identification of Itch loss-of-function mutant mice (itchy). Mutant mice display an autoimmune-like phenotype characterized by chronic dermatitis, which has been attributed to increas...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2016-02, Vol.241 (4), p.367
Hauptverfasser:	Stermer, Angela R, Myers, Jessica L, Murphy, Caitlin J, Di Bona, Kristin R, Matesic, Lydia, Richburg, John H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Estrous Cycle Female Humans Male Mice, Inbred C57BL Reproduction Ubiquitin-Protein Ligases - deficiency Ubiquitin-Protein Ligases - metabolism
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