Epigenetic regulation of dorsal raphe GABA(B1a) associated with isolation-induced abnormal responses to social stimulation in mice

In isolation-reared mice, social encounter stimulation induces locomotor hyperactivity and activation of the dorsal raphe nucleus (DRN), suggesting that dysregulation of dorsal raphe function may be involved in abnormal behaviors. In this study, we examined the involvement of dorsal raphe GABAergic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuropharmacology 2016-02, Vol.101, p.1
Hauptverfasser:	Araki, Ryota, Hiraki, Yosuke, Nishida, Shoji, Kuramoto, Nobuyuki, Matsumoto, Kinzo, Yabe, Takeshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggression - physiology Animals Chromatin Immunoprecipitation DNA Methylation - drug effects Dorsal Raphe Nucleus - drug effects Dorsal Raphe Nucleus - metabolism Epigenesis, Genetic - drug effects Epigenesis, Genetic - physiology GABA Agents - pharmacology Glutamate Decarboxylase - genetics Glutamate Decarboxylase - metabolism Glycine - analogs & derivatives Glycine - metabolism Male Mental Disorders - etiology Mental Disorders - genetics Mice Mice, Inbred ICR Motor Activity Protein Subunits - genetics Protein Subunits - metabolism Receptors, GABA-A - genetics Receptors, GABA-A - metabolism Receptors, GABA-B - genetics Receptors, GABA-B - metabolism Social Isolation - psychology Swimming - psychology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!