Influenza vaccine effectiveness among healthcare workers in comparison to hospitalized patients: A 2004-2009 case-test, negative-control, prospective study
The objective of this study was to calculate Vaccine Effectiveness (VE) in healthcare workers (HCW) and to compare VE between patients and HCW. A case-control investigation based on the prospective study was conducted between 2004 and 2009 in a teaching hospital. All HCW with influenza-like illness...
Gespeichert in:
| Veröffentlicht in: | Human vaccines & immunotherapeutics 2016-02, Vol.12 (2), p.485-490 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 490 |
|---|---|
| container_issue | 2 |
| container_start_page | 485 |
| container_title | Human vaccines & immunotherapeutics |
| container_volume | 12 |
| creator | Vanhems, P Baghdadi, Y Roche, S Bénet, T Regis, C Lina, B Robert, O Voirin, N Ecochard, R Amour, S |
| description | The objective of this study was to calculate Vaccine Effectiveness (VE) in healthcare workers (HCW) and to compare VE between patients and HCW. A case-control investigation based on the prospective study was conducted between 2004 and 2009 in a teaching hospital. All HCW with influenza-like illness (ILI) from participating units (n = 24) were included, and vaccination status was characterized by interview. A total of 150 HCW presented ILI; 130 (87%) were female, 27 (18%) were positive for influenza, and 42 (28%) were vaccinated. Adjusted VE was 89% (95% CI 39 to 98). Among patients, adjusted VE was 42% (95% CI −39 to 76). The difference of VE (VE
hcw
- VE
pat
) was 46.15% (95% CI 2.41 to 144). The VE ratio (VE
hcw
/ VE
pat
) was 2.09 (95% CI −1.60 to 134.17). Influenza VE differed between HCW and patients when the flu season was taken into account. This finding confirms the major impact of host determinants on influenza VE. |
| doi_str_mv | 10.1080/21645515.2015.1079677 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_26327520</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1768169342</sourcerecordid><originalsourceid>FETCH-LOGICAL-c502t-e92d1bfa11833828e31fbd39ff0ce2f3ef14b31edd1d5f96bd55f5dc9896ab0d3</originalsourceid><addsrcrecordid>eNp9Uk1v1DAQjRCIVqU_AeQjSE3xR5wPDohVBbTSSlxA4mY59nhjSOxgO4u2f4U_i1e7XQEHfBhb4zfv2TOvKJ4TfE1wi19TUlecE35NcQ4EN13dNI-K832-5Lz6-vh0JvysuIzxG86rwbSq66fFGa0ZbTjF58WvO2fGBdy9RFuplHWAwBhQyW7BQYxITt5t0AByTIOSAdBPH75DiMg6pPw0y2Cjdyh5NPg42yRHew8azTJZcCm-QStEMa7KHDqkZIQyQUxXyMFG7kVK5V0KfrxCc8gEB2UU06J3z4onRo4RLo_7RfHlw_vPN7fl-tPHu5vVulQc01RCRzXpjSSkZaylLTBies06Y7ACahgYUvWMgNZEc9PVvebccK26tqtljzW7KN4eeOeln0Cr_O4gRzEHO8mwE15a8feNs4PY-K3guOoa1mWCVweC4Z-y29Va7HOYZmSW25KMfXkUC_7HklshJhsVjKN04JcoSFO3pO5YRTOUH6AqdyYGMCdugsXeB-LBB2LvA3H0Qa578ed_TlUPU8-AdweAdcaHSeaRjlokuRt9MEE6ZaNg_9f4DQdRxZI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1768169342</pqid></control><display><type>article</type><title>Influenza vaccine effectiveness among healthcare workers in comparison to hospitalized patients: A 2004-2009 case-test, negative-control, prospective study</title><source>MEDLINE</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Vanhems, P ; Baghdadi, Y ; Roche, S ; Bénet, T ; Regis, C ; Lina, B ; Robert, O ; Voirin, N ; Ecochard, R ; Amour, S</creator><creatorcontrib>Vanhems, P ; Baghdadi, Y ; Roche, S ; Bénet, T ; Regis, C ; Lina, B ; Robert, O ; Voirin, N ; Ecochard, R ; Amour, S</creatorcontrib><description>The objective of this study was to calculate Vaccine Effectiveness (VE) in healthcare workers (HCW) and to compare VE between patients and HCW. A case-control investigation based on the prospective study was conducted between 2004 and 2009 in a teaching hospital. All HCW with influenza-like illness (ILI) from participating units (n = 24) were included, and vaccination status was characterized by interview. A total of 150 HCW presented ILI; 130 (87%) were female, 27 (18%) were positive for influenza, and 42 (28%) were vaccinated. Adjusted VE was 89% (95% CI 39 to 98). Among patients, adjusted VE was 42% (95% CI −39 to 76). The difference of VE (VE
hcw
- VE
pat
) was 46.15% (95% CI 2.41 to 144). The VE ratio (VE
hcw
/ VE
pat
) was 2.09 (95% CI −1.60 to 134.17). Influenza VE differed between HCW and patients when the flu season was taken into account. This finding confirms the major impact of host determinants on influenza VE.</description><identifier>ISSN: 2164-5515</identifier><identifier>EISSN: 2164-554X</identifier><identifier>DOI: 10.1080/21645515.2015.1079677</identifier><identifier>PMID: 26327520</identifier><language>eng</language><publisher>United States: Taylor & Francis</publisher><subject>Adult ; Case-Control Studies ; Female ; Health Personnel ; healthcare workers ; Hospitals, Teaching ; Humans ; Immunogenicity, Vaccine - immunology ; Influenza A virus - immunology ; Influenza B virus - immunology ; influenza vaccine effectiveness ; Influenza Vaccines - immunology ; Influenza, Human - epidemiology ; Influenza, Human - prevention & control ; Life Sciences ; Male ; Middle Aged ; Prospective Studies ; Seasonal influenza ; Short Report ; vaccination ; Vaccination - statistics & numerical data</subject><ispartof>Human vaccines & immunotherapeutics, 2016-02, Vol.12 (2), p.485-490</ispartof><rights>2016 Taylor & Francis Group, LLC 2016</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><rights>2016 Taylor & Francis Group, LLC 2016 Taylor & Francis Group, LLC</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c502t-e92d1bfa11833828e31fbd39ff0ce2f3ef14b31edd1d5f96bd55f5dc9896ab0d3</citedby><cites>FETCH-LOGICAL-c502t-e92d1bfa11833828e31fbd39ff0ce2f3ef14b31edd1d5f96bd55f5dc9896ab0d3</cites><orcidid>0000-0002-8959-2123 ; 0000-0002-1695-789X ; 0000-0003-3188-1456</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049739/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049739/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26327520$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://univ-lyon1.hal.science/hal-02049896$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Vanhems, P</creatorcontrib><creatorcontrib>Baghdadi, Y</creatorcontrib><creatorcontrib>Roche, S</creatorcontrib><creatorcontrib>Bénet, T</creatorcontrib><creatorcontrib>Regis, C</creatorcontrib><creatorcontrib>Lina, B</creatorcontrib><creatorcontrib>Robert, O</creatorcontrib><creatorcontrib>Voirin, N</creatorcontrib><creatorcontrib>Ecochard, R</creatorcontrib><creatorcontrib>Amour, S</creatorcontrib><title>Influenza vaccine effectiveness among healthcare workers in comparison to hospitalized patients: A 2004-2009 case-test, negative-control, prospective study</title><title>Human vaccines & immunotherapeutics</title><addtitle>Hum Vaccin Immunother</addtitle><description>The objective of this study was to calculate Vaccine Effectiveness (VE) in healthcare workers (HCW) and to compare VE between patients and HCW. A case-control investigation based on the prospective study was conducted between 2004 and 2009 in a teaching hospital. All HCW with influenza-like illness (ILI) from participating units (n = 24) were included, and vaccination status was characterized by interview. A total of 150 HCW presented ILI; 130 (87%) were female, 27 (18%) were positive for influenza, and 42 (28%) were vaccinated. Adjusted VE was 89% (95% CI 39 to 98). Among patients, adjusted VE was 42% (95% CI −39 to 76). The difference of VE (VE
hcw
- VE
pat
) was 46.15% (95% CI 2.41 to 144). The VE ratio (VE
hcw
/ VE
pat
) was 2.09 (95% CI −1.60 to 134.17). Influenza VE differed between HCW and patients when the flu season was taken into account. This finding confirms the major impact of host determinants on influenza VE.</description><subject>Adult</subject><subject>Case-Control Studies</subject><subject>Female</subject><subject>Health Personnel</subject><subject>healthcare workers</subject><subject>Hospitals, Teaching</subject><subject>Humans</subject><subject>Immunogenicity, Vaccine - immunology</subject><subject>Influenza A virus - immunology</subject><subject>Influenza B virus - immunology</subject><subject>influenza vaccine effectiveness</subject><subject>Influenza Vaccines - immunology</subject><subject>Influenza, Human - epidemiology</subject><subject>Influenza, Human - prevention & control</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Seasonal influenza</subject><subject>Short Report</subject><subject>vaccination</subject><subject>Vaccination - statistics & numerical data</subject><issn>2164-5515</issn><issn>2164-554X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Uk1v1DAQjRCIVqU_AeQjSE3xR5wPDohVBbTSSlxA4mY59nhjSOxgO4u2f4U_i1e7XQEHfBhb4zfv2TOvKJ4TfE1wi19TUlecE35NcQ4EN13dNI-K832-5Lz6-vh0JvysuIzxG86rwbSq66fFGa0ZbTjF58WvO2fGBdy9RFuplHWAwBhQyW7BQYxITt5t0AByTIOSAdBPH75DiMg6pPw0y2Cjdyh5NPg42yRHew8azTJZcCm-QStEMa7KHDqkZIQyQUxXyMFG7kVK5V0KfrxCc8gEB2UU06J3z4onRo4RLo_7RfHlw_vPN7fl-tPHu5vVulQc01RCRzXpjSSkZaylLTBies06Y7ACahgYUvWMgNZEc9PVvebccK26tqtljzW7KN4eeOeln0Cr_O4gRzEHO8mwE15a8feNs4PY-K3guOoa1mWCVweC4Z-y29Va7HOYZmSW25KMfXkUC_7HklshJhsVjKN04JcoSFO3pO5YRTOUH6AqdyYGMCdugsXeB-LBB2LvA3H0Qa578ed_TlUPU8-AdweAdcaHSeaRjlokuRt9MEE6ZaNg_9f4DQdRxZI</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Vanhems, P</creator><creator>Baghdadi, Y</creator><creator>Roche, S</creator><creator>Bénet, T</creator><creator>Regis, C</creator><creator>Lina, B</creator><creator>Robert, O</creator><creator>Voirin, N</creator><creator>Ecochard, R</creator><creator>Amour, S</creator><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-8959-2123</orcidid><orcidid>https://orcid.org/0000-0002-1695-789X</orcidid><orcidid>https://orcid.org/0000-0003-3188-1456</orcidid></search><sort><creationdate>20160201</creationdate><title>Influenza vaccine effectiveness among healthcare workers in comparison to hospitalized patients: A 2004-2009 case-test, negative-control, prospective study</title><author>Vanhems, P ; Baghdadi, Y ; Roche, S ; Bénet, T ; Regis, C ; Lina, B ; Robert, O ; Voirin, N ; Ecochard, R ; Amour, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c502t-e92d1bfa11833828e31fbd39ff0ce2f3ef14b31edd1d5f96bd55f5dc9896ab0d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Case-Control Studies</topic><topic>Female</topic><topic>Health Personnel</topic><topic>healthcare workers</topic><topic>Hospitals, Teaching</topic><topic>Humans</topic><topic>Immunogenicity, Vaccine - immunology</topic><topic>Influenza A virus - immunology</topic><topic>Influenza B virus - immunology</topic><topic>influenza vaccine effectiveness</topic><topic>Influenza Vaccines - immunology</topic><topic>Influenza, Human - epidemiology</topic><topic>Influenza, Human - prevention & control</topic><topic>Life Sciences</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Seasonal influenza</topic><topic>Short Report</topic><topic>vaccination</topic><topic>Vaccination - statistics & numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vanhems, P</creatorcontrib><creatorcontrib>Baghdadi, Y</creatorcontrib><creatorcontrib>Roche, S</creatorcontrib><creatorcontrib>Bénet, T</creatorcontrib><creatorcontrib>Regis, C</creatorcontrib><creatorcontrib>Lina, B</creatorcontrib><creatorcontrib>Robert, O</creatorcontrib><creatorcontrib>Voirin, N</creatorcontrib><creatorcontrib>Ecochard, R</creatorcontrib><creatorcontrib>Amour, S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Human vaccines & immunotherapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vanhems, P</au><au>Baghdadi, Y</au><au>Roche, S</au><au>Bénet, T</au><au>Regis, C</au><au>Lina, B</au><au>Robert, O</au><au>Voirin, N</au><au>Ecochard, R</au><au>Amour, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influenza vaccine effectiveness among healthcare workers in comparison to hospitalized patients: A 2004-2009 case-test, negative-control, prospective study</atitle><jtitle>Human vaccines & immunotherapeutics</jtitle><addtitle>Hum Vaccin Immunother</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>12</volume><issue>2</issue><spage>485</spage><epage>490</epage><pages>485-490</pages><issn>2164-5515</issn><eissn>2164-554X</eissn><abstract>The objective of this study was to calculate Vaccine Effectiveness (VE) in healthcare workers (HCW) and to compare VE between patients and HCW. A case-control investigation based on the prospective study was conducted between 2004 and 2009 in a teaching hospital. All HCW with influenza-like illness (ILI) from participating units (n = 24) were included, and vaccination status was characterized by interview. A total of 150 HCW presented ILI; 130 (87%) were female, 27 (18%) were positive for influenza, and 42 (28%) were vaccinated. Adjusted VE was 89% (95% CI 39 to 98). Among patients, adjusted VE was 42% (95% CI −39 to 76). The difference of VE (VE
hcw
- VE
pat
) was 46.15% (95% CI 2.41 to 144). The VE ratio (VE
hcw
/ VE
pat
) was 2.09 (95% CI −1.60 to 134.17). Influenza VE differed between HCW and patients when the flu season was taken into account. This finding confirms the major impact of host determinants on influenza VE.</abstract><cop>United States</cop><pub>Taylor & Francis</pub><pmid>26327520</pmid><doi>10.1080/21645515.2015.1079677</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-8959-2123</orcidid><orcidid>https://orcid.org/0000-0002-1695-789X</orcidid><orcidid>https://orcid.org/0000-0003-3188-1456</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2164-5515 |
| ispartof | Human vaccines & immunotherapeutics, 2016-02, Vol.12 (2), p.485-490 |
| issn | 2164-5515 2164-554X |
| language | eng |
| recordid | cdi_pubmed_primary_26327520 |
| source | MEDLINE; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Case-Control Studies Female Health Personnel healthcare workers Hospitals, Teaching Humans Immunogenicity, Vaccine - immunology Influenza A virus - immunology Influenza B virus - immunology influenza vaccine effectiveness Influenza Vaccines - immunology Influenza, Human - epidemiology Influenza, Human - prevention & control Life Sciences Male Middle Aged Prospective Studies Seasonal influenza Short Report vaccination Vaccination - statistics & numerical data |
| title | Influenza vaccine effectiveness among healthcare workers in comparison to hospitalized patients: A 2004-2009 case-test, negative-control, prospective study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T11%3A10%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Influenza%20vaccine%20effectiveness%20among%20healthcare%20workers%20in%20comparison%20to%20hospitalized%20patients:%20A%202004-2009%20case-test,%20negative-control,%20prospective%20study&rft.jtitle=Human%20vaccines%20&%20immunotherapeutics&rft.au=Vanhems,%20P&rft.date=2016-02-01&rft.volume=12&rft.issue=2&rft.spage=485&rft.epage=490&rft.pages=485-490&rft.issn=2164-5515&rft.eissn=2164-554X&rft_id=info:doi/10.1080/21645515.2015.1079677&rft_dat=%3Cproquest_pubme%3E1768169342%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1768169342&rft_id=info:pmid/26327520&rfr_iscdi=true |