Low-Dose Atypical Antipsychotic Risperidone Improves the 5-Year Outcome in Alzheimer's Disease Patients with Sleep Disturbances

Sleep disturbances (SD) accelerate the progression of Alzheimer's disease (AD) and increase the stress of caregivers. However, the long-term outcome of disturbed nocturnal sleep/wake patterns in AD and on increased stress of spousal caregivers is unclear. This study assessed the 5-year effect o...

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Veröffentlicht in:	Pharmacology 2015-01, Vol.96 (3-4), p.155-162
Hauptverfasser:	Yin, You, Liu, Yan, Zhuang, Jianhua, Pan, Xiao, Li, Peng, Yang, Yuechang, Li, Yan-Peng, Zhao, Zheng-Qing, Huang, Liu-Qing, Zhao, Zhong-Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - complications Alzheimer Disease - drug therapy Alzheimer Disease - psychology Alzheimer's disease Antipsychotic Agents - administration & dosage Antipsychotic Agents - therapeutic use Caregivers - psychology Circadian rhythm Drug therapy Female Humans Hypnotics and Sedatives - therapeutic use Indans - therapeutic use Insomnia Male Melatonin - therapeutic use Neuropsychological Tests Nootropic Agents - therapeutic use Nursing Homes Original Paper Pharmacology Piperidines - therapeutic use Polysomnography Pyridines - therapeutic use Risperidone - administration & dosage Risperidone - therapeutic use Sleep Sleep Wake Disorders - drug therapy Sleep Wake Disorders - etiology Sleep Wake Disorders - psychology Treatment Outcome
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