POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans
How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand ye...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 2015-08, Vol.349 (6250), p.aab3884 |
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| creator | Raghavan, Maanasa Steinrücken, Matthias Harris, Kelley Schiffels, Stephan Rasmussen, Simon DeGiorgio, Michael Albrechtsen, Anders Valdiosera, Cristina Ávila-Arcos, María C Malaspinas, Anna-Sapfo Eriksson, Anders Moltke, Ida Metspalu, Mait Homburger, Julian R Wall, Jeff Cornejo, Omar E Moreno-Mayar, J Víctor Korneliussen, Thorfinn S Pierre, Tracey Rasmussen, Morten Campos, Paula F de Barros Damgaard, Peter Allentoft, Morten E Lindo, John Metspalu, Ene Rodríguez-Varela, Ricardo Mansilla, Josefina Henrickson, Celeste Seguin-Orlando, Andaine Malmström, Helena Stafford, Jr, Thomas Shringarpure, Suyash S Moreno-Estrada, Andrés Karmin, Monika Tambets, Kristiina Bergström, Anders Xue, Yali Warmuth, Vera Friend, Andrew D Singarayer, Joy Valdes, Paul Balloux, Francois Leboreiro, Ilán Vera, Jose Luis Rangel-Villalobos, Hector Pettener, Davide Luiselli, Donata Davis, Loren G Heyer, Evelyne Zollikofer, Christoph P E Ponce de León, Marcia S Smith, Colin I Grimes, Vaughan Pike, Kelly-Anne Deal, Michael Fuller, Benjamin T Arriaza, Bernardo Standen, Vivien Luz, Maria F Ricaut, Francois Guidon, Niede Osipova, Ludmila Voevoda, Mikhail I Posukh, Olga L Balanovsky, Oleg Lavryashina, Maria Bogunov, Yuri Khusnutdinova, Elza Gubina, Marina Balanovska, Elena Fedorova, Sardana Litvinov, Sergey Malyarchuk, Boris Derenko, Miroslava Mosher, M J Archer, David Cybulski, Jerome Petzelt, Barbara Mitchell, Joycelynn Worl, Rosita Norman, Paul J Parham, Peter Kemp, Brian M Kivisild, Toomas Tyler-Smith, Chris Sandhu, Manjinder S Crawford, Michael Villems, Richard Smith, David Glenn Waters, Michael R Goebel, Ted Johnson, John R Malhi, Ripan S Jakobsson, Mattias Meltzer, David J Manica, Andrea Durbin, Richard Bustamante, Carlos D Song, Yun S Nielsen, Rasmus |
| description | How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model. |
| doi_str_mv | 10.1126/science.aab3884 |
| format | Article |
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Genomic evidence for the Pleistocene and recent population history of Native Americans</title><source>American Association for the Advancement of Science</source><source>Jstor Complete Legacy</source><source>MEDLINE</source><creator>Raghavan, Maanasa ; Steinrücken, Matthias ; Harris, Kelley ; Schiffels, Stephan ; Rasmussen, Simon ; DeGiorgio, Michael ; Albrechtsen, Anders ; Valdiosera, Cristina ; Ávila-Arcos, María C ; Malaspinas, Anna-Sapfo ; Eriksson, Anders ; Moltke, Ida ; Metspalu, Mait ; Homburger, Julian R ; Wall, Jeff ; Cornejo, Omar E ; Moreno-Mayar, J Víctor ; Korneliussen, Thorfinn S ; Pierre, Tracey ; Rasmussen, Morten ; Campos, Paula F ; de Barros Damgaard, Peter ; Allentoft, Morten E ; Lindo, John ; Metspalu, Ene ; Rodríguez-Varela, Ricardo ; Mansilla, Josefina ; Henrickson, Celeste ; Seguin-Orlando, Andaine ; Malmström, Helena ; Stafford, Jr, Thomas ; Shringarpure, Suyash S ; Moreno-Estrada, Andrés ; Karmin, Monika ; Tambets, Kristiina ; Bergström, Anders ; Xue, Yali ; Warmuth, Vera ; Friend, Andrew D ; Singarayer, Joy ; Valdes, Paul ; Balloux, Francois ; Leboreiro, Ilán ; Vera, Jose Luis ; Rangel-Villalobos, Hector ; Pettener, Davide ; Luiselli, Donata ; Davis, Loren G ; Heyer, Evelyne ; Zollikofer, Christoph P E ; Ponce de León, Marcia S ; Smith, Colin I ; Grimes, Vaughan ; Pike, Kelly-Anne ; Deal, Michael ; Fuller, Benjamin T ; Arriaza, Bernardo ; Standen, Vivien ; Luz, Maria F ; Ricaut, Francois ; Guidon, Niede ; Osipova, Ludmila ; Voevoda, Mikhail I ; Posukh, Olga L ; Balanovsky, Oleg ; Lavryashina, Maria ; Bogunov, Yuri ; Khusnutdinova, Elza ; Gubina, Marina ; Balanovska, Elena ; Fedorova, Sardana ; Litvinov, Sergey ; Malyarchuk, Boris ; Derenko, Miroslava ; Mosher, M J ; Archer, David ; Cybulski, Jerome ; Petzelt, Barbara ; Mitchell, Joycelynn ; Worl, Rosita ; Norman, Paul J ; Parham, Peter ; Kemp, Brian M ; Kivisild, Toomas ; Tyler-Smith, Chris ; Sandhu, Manjinder S ; Crawford, Michael ; Villems, Richard ; Smith, David Glenn ; Waters, Michael R ; Goebel, Ted ; Johnson, John R ; Malhi, Ripan S ; Jakobsson, Mattias ; Meltzer, David J ; Manica, Andrea ; Durbin, Richard ; Bustamante, Carlos D ; Song, Yun S ; Nielsen, Rasmus</creator><creatorcontrib>Raghavan, Maanasa ; Steinrücken, Matthias ; Harris, Kelley ; Schiffels, Stephan ; Rasmussen, Simon ; DeGiorgio, Michael ; Albrechtsen, Anders ; Valdiosera, Cristina ; Ávila-Arcos, María C ; Malaspinas, Anna-Sapfo ; Eriksson, Anders ; Moltke, Ida ; Metspalu, Mait ; Homburger, Julian R ; Wall, Jeff ; Cornejo, Omar E ; Moreno-Mayar, J Víctor ; Korneliussen, Thorfinn S ; Pierre, Tracey ; Rasmussen, Morten ; Campos, Paula F ; de Barros Damgaard, Peter ; Allentoft, Morten E ; Lindo, John ; Metspalu, Ene ; Rodríguez-Varela, Ricardo ; Mansilla, Josefina ; Henrickson, Celeste ; Seguin-Orlando, Andaine ; Malmström, Helena ; Stafford, Jr, Thomas ; Shringarpure, Suyash S ; Moreno-Estrada, Andrés ; Karmin, Monika ; Tambets, Kristiina ; Bergström, Anders ; Xue, Yali ; Warmuth, Vera ; Friend, Andrew D ; Singarayer, Joy ; Valdes, Paul ; Balloux, Francois ; Leboreiro, Ilán ; Vera, Jose Luis ; Rangel-Villalobos, Hector ; Pettener, Davide ; Luiselli, Donata ; Davis, Loren G ; Heyer, Evelyne ; Zollikofer, Christoph P E ; Ponce de León, Marcia S ; Smith, Colin I ; Grimes, Vaughan ; Pike, Kelly-Anne ; Deal, Michael ; Fuller, Benjamin T ; Arriaza, Bernardo ; Standen, Vivien ; Luz, Maria F ; Ricaut, Francois ; Guidon, Niede ; Osipova, Ludmila ; Voevoda, Mikhail I ; Posukh, Olga L ; Balanovsky, Oleg ; Lavryashina, Maria ; Bogunov, Yuri ; Khusnutdinova, Elza ; Gubina, Marina ; Balanovska, Elena ; Fedorova, Sardana ; Litvinov, Sergey ; Malyarchuk, Boris ; Derenko, Miroslava ; Mosher, M J ; Archer, David ; Cybulski, Jerome ; Petzelt, Barbara ; Mitchell, Joycelynn ; Worl, Rosita ; Norman, Paul J ; Parham, Peter ; Kemp, Brian M ; Kivisild, Toomas ; Tyler-Smith, Chris ; Sandhu, Manjinder S ; Crawford, Michael ; Villems, Richard ; Smith, David Glenn ; Waters, Michael R ; Goebel, Ted ; Johnson, John R ; Malhi, Ripan S ; Jakobsson, Mattias ; Meltzer, David J ; Manica, Andrea ; Durbin, Richard ; Bustamante, Carlos D ; Song, Yun S ; Nielsen, Rasmus</creatorcontrib><description>How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model.</description><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.aab3884</identifier><identifier>PMID: 26198033</identifier><language>eng</language><publisher>United States</publisher><subject>Americas ; Gene Flow ; Genomics ; History, Ancient ; Human Migration - history ; Humans ; Indians, North American - genetics ; Indians, North American - history ; Models, Genetic ; Siberia</subject><ispartof>Science (American Association for the Advancement of Science), 2015-08, Vol.349 (6250), p.aab3884</ispartof><rights>Copyright © 2015, American Association for the Advancement of 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Genomic evidence for the Pleistocene and recent population history of Native Americans</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. 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Genomic evidence for the Pleistocene and recent population history of Native Americans</title><author>Raghavan, Maanasa ; Steinrücken, Matthias ; Harris, Kelley ; Schiffels, Stephan ; Rasmussen, Simon ; DeGiorgio, Michael ; Albrechtsen, Anders ; Valdiosera, Cristina ; Ávila-Arcos, María C ; Malaspinas, Anna-Sapfo ; Eriksson, Anders ; Moltke, Ida ; Metspalu, Mait ; Homburger, Julian R ; Wall, Jeff ; Cornejo, Omar E ; Moreno-Mayar, J Víctor ; Korneliussen, Thorfinn S ; Pierre, Tracey ; Rasmussen, Morten ; Campos, Paula F ; de Barros Damgaard, Peter ; Allentoft, Morten E ; Lindo, John ; Metspalu, Ene ; Rodríguez-Varela, Ricardo ; Mansilla, Josefina ; Henrickson, Celeste ; Seguin-Orlando, Andaine ; Malmström, Helena ; Stafford, Jr, Thomas ; Shringarpure, Suyash S ; Moreno-Estrada, Andrés ; Karmin, Monika ; Tambets, Kristiina ; Bergström, Anders ; Xue, Yali ; Warmuth, Vera ; Friend, Andrew D ; Singarayer, Joy ; Valdes, Paul ; Balloux, Francois ; Leboreiro, Ilán ; Vera, Jose Luis ; Rangel-Villalobos, Hector ; Pettener, Davide ; Luiselli, Donata ; Davis, Loren G ; Heyer, Evelyne ; Zollikofer, Christoph P E ; Ponce de León, Marcia S ; Smith, Colin I ; Grimes, Vaughan ; Pike, Kelly-Anne ; Deal, Michael ; Fuller, Benjamin T ; Arriaza, Bernardo ; Standen, Vivien ; Luz, Maria F ; Ricaut, Francois ; Guidon, Niede ; Osipova, Ludmila ; Voevoda, Mikhail I ; Posukh, Olga L ; Balanovsky, Oleg ; Lavryashina, Maria ; Bogunov, Yuri ; Khusnutdinova, Elza ; Gubina, Marina ; Balanovska, Elena ; Fedorova, Sardana ; Litvinov, Sergey ; Malyarchuk, Boris ; Derenko, Miroslava ; Mosher, M J ; Archer, David ; Cybulski, Jerome ; Petzelt, Barbara ; Mitchell, Joycelynn ; Worl, Rosita ; Norman, Paul J ; Parham, Peter ; Kemp, Brian M ; Kivisild, Toomas ; Tyler-Smith, Chris ; Sandhu, Manjinder S ; Crawford, Michael ; Villems, Richard ; Smith, David Glenn ; Waters, Michael R ; Goebel, Ted ; Johnson, John R ; Malhi, Ripan S ; Jakobsson, Mattias ; Meltzer, David J ; Manica, Andrea ; Durbin, Richard ; Bustamante, Carlos D ; Song, Yun S ; Nielsen, Rasmus</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p563-5af4b65fa6ce079da73448ed1a211444b1c0d4819c238e0aede01ae82139f9863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Americas</topic><topic>Gene Flow</topic><topic>Genomics</topic><topic>History, Ancient</topic><topic>Human Migration - history</topic><topic>Humans</topic><topic>Indians, North American - genetics</topic><topic>Indians, North American - history</topic><topic>Models, Genetic</topic><topic>Siberia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Raghavan, Maanasa</creatorcontrib><creatorcontrib>Steinrücken, Matthias</creatorcontrib><creatorcontrib>Harris, Kelley</creatorcontrib><creatorcontrib>Schiffels, Stephan</creatorcontrib><creatorcontrib>Rasmussen, Simon</creatorcontrib><creatorcontrib>DeGiorgio, Michael</creatorcontrib><creatorcontrib>Albrechtsen, Anders</creatorcontrib><creatorcontrib>Valdiosera, Cristina</creatorcontrib><creatorcontrib>Ávila-Arcos, María C</creatorcontrib><creatorcontrib>Malaspinas, Anna-Sapfo</creatorcontrib><creatorcontrib>Eriksson, Anders</creatorcontrib><creatorcontrib>Moltke, Ida</creatorcontrib><creatorcontrib>Metspalu, Mait</creatorcontrib><creatorcontrib>Homburger, Julian R</creatorcontrib><creatorcontrib>Wall, Jeff</creatorcontrib><creatorcontrib>Cornejo, Omar E</creatorcontrib><creatorcontrib>Moreno-Mayar, J Víctor</creatorcontrib><creatorcontrib>Korneliussen, Thorfinn S</creatorcontrib><creatorcontrib>Pierre, Tracey</creatorcontrib><creatorcontrib>Rasmussen, Morten</creatorcontrib><creatorcontrib>Campos, Paula F</creatorcontrib><creatorcontrib>de Barros Damgaard, Peter</creatorcontrib><creatorcontrib>Allentoft, Morten E</creatorcontrib><creatorcontrib>Lindo, John</creatorcontrib><creatorcontrib>Metspalu, Ene</creatorcontrib><creatorcontrib>Rodríguez-Varela, Ricardo</creatorcontrib><creatorcontrib>Mansilla, Josefina</creatorcontrib><creatorcontrib>Henrickson, Celeste</creatorcontrib><creatorcontrib>Seguin-Orlando, Andaine</creatorcontrib><creatorcontrib>Malmström, Helena</creatorcontrib><creatorcontrib>Stafford, Jr, Thomas</creatorcontrib><creatorcontrib>Shringarpure, Suyash S</creatorcontrib><creatorcontrib>Moreno-Estrada, Andrés</creatorcontrib><creatorcontrib>Karmin, Monika</creatorcontrib><creatorcontrib>Tambets, Kristiina</creatorcontrib><creatorcontrib>Bergström, Anders</creatorcontrib><creatorcontrib>Xue, Yali</creatorcontrib><creatorcontrib>Warmuth, Vera</creatorcontrib><creatorcontrib>Friend, Andrew D</creatorcontrib><creatorcontrib>Singarayer, Joy</creatorcontrib><creatorcontrib>Valdes, Paul</creatorcontrib><creatorcontrib>Balloux, Francois</creatorcontrib><creatorcontrib>Leboreiro, Ilán</creatorcontrib><creatorcontrib>Vera, Jose Luis</creatorcontrib><creatorcontrib>Rangel-Villalobos, Hector</creatorcontrib><creatorcontrib>Pettener, Davide</creatorcontrib><creatorcontrib>Luiselli, Donata</creatorcontrib><creatorcontrib>Davis, Loren G</creatorcontrib><creatorcontrib>Heyer, Evelyne</creatorcontrib><creatorcontrib>Zollikofer, Christoph P E</creatorcontrib><creatorcontrib>Ponce de León, Marcia S</creatorcontrib><creatorcontrib>Smith, Colin I</creatorcontrib><creatorcontrib>Grimes, Vaughan</creatorcontrib><creatorcontrib>Pike, Kelly-Anne</creatorcontrib><creatorcontrib>Deal, Michael</creatorcontrib><creatorcontrib>Fuller, Benjamin T</creatorcontrib><creatorcontrib>Arriaza, Bernardo</creatorcontrib><creatorcontrib>Standen, Vivien</creatorcontrib><creatorcontrib>Luz, Maria F</creatorcontrib><creatorcontrib>Ricaut, Francois</creatorcontrib><creatorcontrib>Guidon, Niede</creatorcontrib><creatorcontrib>Osipova, Ludmila</creatorcontrib><creatorcontrib>Voevoda, Mikhail I</creatorcontrib><creatorcontrib>Posukh, Olga L</creatorcontrib><creatorcontrib>Balanovsky, Oleg</creatorcontrib><creatorcontrib>Lavryashina, Maria</creatorcontrib><creatorcontrib>Bogunov, Yuri</creatorcontrib><creatorcontrib>Khusnutdinova, Elza</creatorcontrib><creatorcontrib>Gubina, Marina</creatorcontrib><creatorcontrib>Balanovska, Elena</creatorcontrib><creatorcontrib>Fedorova, Sardana</creatorcontrib><creatorcontrib>Litvinov, Sergey</creatorcontrib><creatorcontrib>Malyarchuk, Boris</creatorcontrib><creatorcontrib>Derenko, Miroslava</creatorcontrib><creatorcontrib>Mosher, M J</creatorcontrib><creatorcontrib>Archer, David</creatorcontrib><creatorcontrib>Cybulski, Jerome</creatorcontrib><creatorcontrib>Petzelt, Barbara</creatorcontrib><creatorcontrib>Mitchell, Joycelynn</creatorcontrib><creatorcontrib>Worl, Rosita</creatorcontrib><creatorcontrib>Norman, Paul J</creatorcontrib><creatorcontrib>Parham, Peter</creatorcontrib><creatorcontrib>Kemp, Brian M</creatorcontrib><creatorcontrib>Kivisild, Toomas</creatorcontrib><creatorcontrib>Tyler-Smith, Chris</creatorcontrib><creatorcontrib>Sandhu, Manjinder S</creatorcontrib><creatorcontrib>Crawford, Michael</creatorcontrib><creatorcontrib>Villems, Richard</creatorcontrib><creatorcontrib>Smith, David Glenn</creatorcontrib><creatorcontrib>Waters, Michael R</creatorcontrib><creatorcontrib>Goebel, Ted</creatorcontrib><creatorcontrib>Johnson, John R</creatorcontrib><creatorcontrib>Malhi, Ripan S</creatorcontrib><creatorcontrib>Jakobsson, Mattias</creatorcontrib><creatorcontrib>Meltzer, David J</creatorcontrib><creatorcontrib>Manica, Andrea</creatorcontrib><creatorcontrib>Durbin, Richard</creatorcontrib><creatorcontrib>Bustamante, Carlos D</creatorcontrib><creatorcontrib>Song, Yun S</creatorcontrib><creatorcontrib>Nielsen, Rasmus</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Raghavan, Maanasa</au><au>Steinrücken, Matthias</au><au>Harris, Kelley</au><au>Schiffels, Stephan</au><au>Rasmussen, Simon</au><au>DeGiorgio, Michael</au><au>Albrechtsen, Anders</au><au>Valdiosera, Cristina</au><au>Ávila-Arcos, María C</au><au>Malaspinas, Anna-Sapfo</au><au>Eriksson, Anders</au><au>Moltke, Ida</au><au>Metspalu, Mait</au><au>Homburger, Julian R</au><au>Wall, Jeff</au><au>Cornejo, Omar E</au><au>Moreno-Mayar, J Víctor</au><au>Korneliussen, Thorfinn S</au><au>Pierre, Tracey</au><au>Rasmussen, Morten</au><au>Campos, Paula F</au><au>de Barros Damgaard, Peter</au><au>Allentoft, Morten E</au><au>Lindo, John</au><au>Metspalu, Ene</au><au>Rodríguez-Varela, Ricardo</au><au>Mansilla, Josefina</au><au>Henrickson, Celeste</au><au>Seguin-Orlando, Andaine</au><au>Malmström, Helena</au><au>Stafford, Jr, Thomas</au><au>Shringarpure, Suyash S</au><au>Moreno-Estrada, Andrés</au><au>Karmin, Monika</au><au>Tambets, Kristiina</au><au>Bergström, Anders</au><au>Xue, Yali</au><au>Warmuth, Vera</au><au>Friend, Andrew D</au><au>Singarayer, Joy</au><au>Valdes, Paul</au><au>Balloux, Francois</au><au>Leboreiro, Ilán</au><au>Vera, Jose Luis</au><au>Rangel-Villalobos, Hector</au><au>Pettener, Davide</au><au>Luiselli, Donata</au><au>Davis, Loren G</au><au>Heyer, Evelyne</au><au>Zollikofer, Christoph P E</au><au>Ponce de León, Marcia S</au><au>Smith, Colin I</au><au>Grimes, Vaughan</au><au>Pike, Kelly-Anne</au><au>Deal, Michael</au><au>Fuller, Benjamin T</au><au>Arriaza, Bernardo</au><au>Standen, Vivien</au><au>Luz, Maria F</au><au>Ricaut, Francois</au><au>Guidon, Niede</au><au>Osipova, Ludmila</au><au>Voevoda, Mikhail I</au><au>Posukh, Olga L</au><au>Balanovsky, Oleg</au><au>Lavryashina, Maria</au><au>Bogunov, Yuri</au><au>Khusnutdinova, Elza</au><au>Gubina, Marina</au><au>Balanovska, Elena</au><au>Fedorova, Sardana</au><au>Litvinov, Sergey</au><au>Malyarchuk, Boris</au><au>Derenko, Miroslava</au><au>Mosher, M J</au><au>Archer, David</au><au>Cybulski, Jerome</au><au>Petzelt, Barbara</au><au>Mitchell, Joycelynn</au><au>Worl, Rosita</au><au>Norman, Paul J</au><au>Parham, Peter</au><au>Kemp, Brian M</au><au>Kivisild, Toomas</au><au>Tyler-Smith, Chris</au><au>Sandhu, Manjinder S</au><au>Crawford, Michael</au><au>Villems, Richard</au><au>Smith, David Glenn</au><au>Waters, Michael R</au><au>Goebel, Ted</au><au>Johnson, John R</au><au>Malhi, Ripan S</au><au>Jakobsson, Mattias</au><au>Meltzer, David J</au><au>Manica, Andrea</au><au>Durbin, Richard</au><au>Bustamante, Carlos D</au><au>Song, Yun S</au><au>Nielsen, Rasmus</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>2015-08-21</date><risdate>2015</risdate><volume>349</volume><issue>6250</issue><spage>aab3884</spage><pages>aab3884-</pages><eissn>1095-9203</eissn><abstract>How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model.</abstract><cop>United States</cop><pmid>26198033</pmid><doi>10.1126/science.aab3884</doi></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 1095-9203 |
| ispartof | Science (American Association for the Advancement of Science), 2015-08, Vol.349 (6250), p.aab3884 |
| issn | 1095-9203 |
| language | eng |
| recordid | cdi_pubmed_primary_26198033 |
| source | American Association for the Advancement of Science; Jstor Complete Legacy; MEDLINE |
| subjects | Americas Gene Flow Genomics History, Ancient Human Migration - history Humans Indians, North American - genetics Indians, North American - history Models, Genetic Siberia |
| title | POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans |
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