Maternal and fetal outcome in Mexican women with rheumatoid arthritis
To report our experience in maternal-fetal outcome in women with RA in a national medical referral center. A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such...
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Veröffentlicht in: | Revista médica (Mexico : 1983) 2015, Vol.53 Suppl 1, p.S24 |
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container_title | Revista médica (Mexico : 1983) |
container_volume | 53 Suppl 1 |
creator | Saavedra, Miguel A Sánchez, Antonio Bustamante, Reyna Miranda-Hernández, Dafhne Soliz-Antezana, Jimena Cruz-Domínguez, Pilar Morales, Sara Jara, Luis J |
description | To report our experience in maternal-fetal outcome in women with RA in a national medical referral center.
A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such as disease activity, preclampsia/eclampsia, rate of live births, abortions, stillbirths, preterm birth, weeks of gestation, birth weight, congenital malformations and use of anti-rheumatic drugs were studied.
We included 73 pregnancies in 72 patients. Disease activity was documented in 47.2% of patients during pregnancy and/or postpartum and 87.7% of patients received some antirheumatic drug. Preclampsia developed in 8.2% of cases. The live birth rate was 98.6%, with preterm delivery in 15.9% and low weight at term in 17.6% of cases. Cesarean section was performed in 77.1% of cases. The disease activity was not associated with a higher percentage of maternal-fetal complications.
Our study showed that most patients do not experience significant activity of RA during pregnancy, fetal outcome is satisfactory and disease activity did not appear to influence significantly the obstetric outcome. |
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A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such as disease activity, preclampsia/eclampsia, rate of live births, abortions, stillbirths, preterm birth, weeks of gestation, birth weight, congenital malformations and use of anti-rheumatic drugs were studied.
We included 73 pregnancies in 72 patients. Disease activity was documented in 47.2% of patients during pregnancy and/or postpartum and 87.7% of patients received some antirheumatic drug. Preclampsia developed in 8.2% of cases. The live birth rate was 98.6%, with preterm delivery in 15.9% and low weight at term in 17.6% of cases. Cesarean section was performed in 77.1% of cases. The disease activity was not associated with a higher percentage of maternal-fetal complications.
Our study showed that most patients do not experience significant activity of RA during pregnancy, fetal outcome is satisfactory and disease activity did not appear to influence significantly the obstetric outcome.</description><identifier>ISSN: 0443-5117</identifier><identifier>PMID: 26020659</identifier><language>spa</language><publisher>Mexico</publisher><subject>Abortion, Spontaneous - epidemiology ; Abortion, Spontaneous - etiology ; Adult ; Antirheumatic Agents - therapeutic use ; Arthritis, Rheumatoid - drug therapy ; Cesarean Section - statistics & numerical data ; Congenital Abnormalities - epidemiology ; Congenital Abnormalities - etiology ; Female ; Fetal Growth Retardation - epidemiology ; Fetal Growth Retardation - etiology ; Follow-Up Studies ; Humans ; Infant, Newborn ; Mexico ; Pre-Eclampsia - epidemiology ; Pre-Eclampsia - etiology ; Pregnancy ; Pregnancy Complications - drug therapy ; Pregnancy Outcome ; Premature Birth - epidemiology ; Premature Birth - etiology ; Retrospective Studies ; Stillbirth - epidemiology</subject><ispartof>Revista médica (Mexico : 1983), 2015, Vol.53 Suppl 1, p.S24</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26020659$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saavedra, Miguel A</creatorcontrib><creatorcontrib>Sánchez, Antonio</creatorcontrib><creatorcontrib>Bustamante, Reyna</creatorcontrib><creatorcontrib>Miranda-Hernández, Dafhne</creatorcontrib><creatorcontrib>Soliz-Antezana, Jimena</creatorcontrib><creatorcontrib>Cruz-Domínguez, Pilar</creatorcontrib><creatorcontrib>Morales, Sara</creatorcontrib><creatorcontrib>Jara, Luis J</creatorcontrib><title>Maternal and fetal outcome in Mexican women with rheumatoid arthritis</title><title>Revista médica (Mexico : 1983)</title><addtitle>Rev Med Inst Mex Seguro Soc</addtitle><description>To report our experience in maternal-fetal outcome in women with RA in a national medical referral center.
A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such as disease activity, preclampsia/eclampsia, rate of live births, abortions, stillbirths, preterm birth, weeks of gestation, birth weight, congenital malformations and use of anti-rheumatic drugs were studied.
We included 73 pregnancies in 72 patients. Disease activity was documented in 47.2% of patients during pregnancy and/or postpartum and 87.7% of patients received some antirheumatic drug. Preclampsia developed in 8.2% of cases. The live birth rate was 98.6%, with preterm delivery in 15.9% and low weight at term in 17.6% of cases. Cesarean section was performed in 77.1% of cases. The disease activity was not associated with a higher percentage of maternal-fetal complications.
Our study showed that most patients do not experience significant activity of RA during pregnancy, fetal outcome is satisfactory and disease activity did not appear to influence significantly the obstetric outcome.</description><subject>Abortion, Spontaneous - epidemiology</subject><subject>Abortion, Spontaneous - etiology</subject><subject>Adult</subject><subject>Antirheumatic Agents - therapeutic use</subject><subject>Arthritis, Rheumatoid - drug therapy</subject><subject>Cesarean Section - statistics & numerical data</subject><subject>Congenital Abnormalities - epidemiology</subject><subject>Congenital Abnormalities - etiology</subject><subject>Female</subject><subject>Fetal Growth Retardation - epidemiology</subject><subject>Fetal Growth Retardation - etiology</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Mexico</subject><subject>Pre-Eclampsia - epidemiology</subject><subject>Pre-Eclampsia - etiology</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - drug therapy</subject><subject>Pregnancy Outcome</subject><subject>Premature Birth - epidemiology</subject><subject>Premature Birth - etiology</subject><subject>Retrospective Studies</subject><subject>Stillbirth - epidemiology</subject><issn>0443-5117</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFjcsOgjAQRbvQCD5-wfQHSMqr6tpg3LBzT0YYwhhaSDtE_XtZ6NrNvecmJ7kLEaosS6M8jg-BWHv_UCrTKj2uRJBolSidn0JRlMDoLPQSbCNb5JmGievBoCQrS3xRDVY-5z0ncSddh5MBHqiR4LhzxOS3YtlC73H37Y3YX4rb-RqN091gU42ODLh39ftN_wofARg4iA</recordid><startdate>2015</startdate><enddate>2015</enddate><creator>Saavedra, Miguel A</creator><creator>Sánchez, Antonio</creator><creator>Bustamante, Reyna</creator><creator>Miranda-Hernández, Dafhne</creator><creator>Soliz-Antezana, Jimena</creator><creator>Cruz-Domínguez, Pilar</creator><creator>Morales, Sara</creator><creator>Jara, Luis J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>2015</creationdate><title>Maternal and fetal outcome in Mexican women with rheumatoid arthritis</title><author>Saavedra, Miguel A ; Sánchez, Antonio ; Bustamante, Reyna ; Miranda-Hernández, Dafhne ; Soliz-Antezana, Jimena ; Cruz-Domínguez, Pilar ; Morales, Sara ; Jara, Luis J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_260206593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2015</creationdate><topic>Abortion, Spontaneous - epidemiology</topic><topic>Abortion, Spontaneous - etiology</topic><topic>Adult</topic><topic>Antirheumatic Agents - therapeutic use</topic><topic>Arthritis, Rheumatoid - drug therapy</topic><topic>Cesarean Section - statistics & numerical data</topic><topic>Congenital Abnormalities - epidemiology</topic><topic>Congenital Abnormalities - etiology</topic><topic>Female</topic><topic>Fetal Growth Retardation - epidemiology</topic><topic>Fetal Growth Retardation - etiology</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Mexico</topic><topic>Pre-Eclampsia - epidemiology</topic><topic>Pre-Eclampsia - etiology</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - drug therapy</topic><topic>Pregnancy Outcome</topic><topic>Premature Birth - epidemiology</topic><topic>Premature Birth - etiology</topic><topic>Retrospective Studies</topic><topic>Stillbirth - epidemiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Saavedra, Miguel A</creatorcontrib><creatorcontrib>Sánchez, Antonio</creatorcontrib><creatorcontrib>Bustamante, Reyna</creatorcontrib><creatorcontrib>Miranda-Hernández, Dafhne</creatorcontrib><creatorcontrib>Soliz-Antezana, Jimena</creatorcontrib><creatorcontrib>Cruz-Domínguez, Pilar</creatorcontrib><creatorcontrib>Morales, Sara</creatorcontrib><creatorcontrib>Jara, Luis J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Revista médica (Mexico : 1983)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saavedra, Miguel A</au><au>Sánchez, Antonio</au><au>Bustamante, Reyna</au><au>Miranda-Hernández, Dafhne</au><au>Soliz-Antezana, Jimena</au><au>Cruz-Domínguez, Pilar</au><au>Morales, Sara</au><au>Jara, Luis J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Maternal and fetal outcome in Mexican women with rheumatoid arthritis</atitle><jtitle>Revista médica (Mexico : 1983)</jtitle><addtitle>Rev Med Inst Mex Seguro Soc</addtitle><date>2015</date><risdate>2015</risdate><volume>53 Suppl 1</volume><spage>S24</spage><pages>S24-</pages><issn>0443-5117</issn><abstract>To report our experience in maternal-fetal outcome in women with RA in a national medical referral center.
A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such as disease activity, preclampsia/eclampsia, rate of live births, abortions, stillbirths, preterm birth, weeks of gestation, birth weight, congenital malformations and use of anti-rheumatic drugs were studied.
We included 73 pregnancies in 72 patients. Disease activity was documented in 47.2% of patients during pregnancy and/or postpartum and 87.7% of patients received some antirheumatic drug. Preclampsia developed in 8.2% of cases. The live birth rate was 98.6%, with preterm delivery in 15.9% and low weight at term in 17.6% of cases. Cesarean section was performed in 77.1% of cases. The disease activity was not associated with a higher percentage of maternal-fetal complications.
Our study showed that most patients do not experience significant activity of RA during pregnancy, fetal outcome is satisfactory and disease activity did not appear to influence significantly the obstetric outcome.</abstract><cop>Mexico</cop><pmid>26020659</pmid></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Abortion, Spontaneous - epidemiology Abortion, Spontaneous - etiology Adult Antirheumatic Agents - therapeutic use Arthritis, Rheumatoid - drug therapy Cesarean Section - statistics & numerical data Congenital Abnormalities - epidemiology Congenital Abnormalities - etiology Female Fetal Growth Retardation - epidemiology Fetal Growth Retardation - etiology Follow-Up Studies Humans Infant, Newborn Mexico Pre-Eclampsia - epidemiology Pre-Eclampsia - etiology Pregnancy Pregnancy Complications - drug therapy Pregnancy Outcome Premature Birth - epidemiology Premature Birth - etiology Retrospective Studies Stillbirth - epidemiology |
title | Maternal and fetal outcome in Mexican women with rheumatoid arthritis |
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