Maternal and fetal outcome in Mexican women with rheumatoid arthritis

To report our experience in maternal-fetal outcome in women with RA in a national medical referral center. A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such...

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Veröffentlicht in:Revista médica (Mexico : 1983) 2015, Vol.53 Suppl 1, p.S24
Hauptverfasser: Saavedra, Miguel A, Sánchez, Antonio, Bustamante, Reyna, Miranda-Hernández, Dafhne, Soliz-Antezana, Jimena, Cruz-Domínguez, Pilar, Morales, Sara, Jara, Luis J
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container_issue
container_start_page S24
container_title Revista médica (Mexico : 1983)
container_volume 53 Suppl 1
creator Saavedra, Miguel A
Sánchez, Antonio
Bustamante, Reyna
Miranda-Hernández, Dafhne
Soliz-Antezana, Jimena
Cruz-Domínguez, Pilar
Morales, Sara
Jara, Luis J
description To report our experience in maternal-fetal outcome in women with RA in a national medical referral center. A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such as disease activity, preclampsia/eclampsia, rate of live births, abortions, stillbirths, preterm birth, weeks of gestation, birth weight, congenital malformations and use of anti-rheumatic drugs were studied. We included 73 pregnancies in 72 patients. Disease activity was documented in 47.2% of patients during pregnancy and/or postpartum and 87.7% of patients received some antirheumatic drug. Preclampsia developed in 8.2% of cases. The live birth rate was 98.6%, with preterm delivery in 15.9% and low weight at term in 17.6% of cases. Cesarean section was performed in 77.1% of cases. The disease activity was not associated with a higher percentage of maternal-fetal complications. Our study showed that most patients do not experience significant activity of RA during pregnancy, fetal outcome is satisfactory and disease activity did not appear to influence significantly the obstetric outcome.
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A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such as disease activity, preclampsia/eclampsia, rate of live births, abortions, stillbirths, preterm birth, weeks of gestation, birth weight, congenital malformations and use of anti-rheumatic drugs were studied. We included 73 pregnancies in 72 patients. Disease activity was documented in 47.2% of patients during pregnancy and/or postpartum and 87.7% of patients received some antirheumatic drug. Preclampsia developed in 8.2% of cases. The live birth rate was 98.6%, with preterm delivery in 15.9% and low weight at term in 17.6% of cases. Cesarean section was performed in 77.1% of cases. The disease activity was not associated with a higher percentage of maternal-fetal complications. 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subjects Abortion, Spontaneous - epidemiology
Abortion, Spontaneous - etiology
Adult
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - drug therapy
Cesarean Section - statistics & numerical data
Congenital Abnormalities - epidemiology
Congenital Abnormalities - etiology
Female
Fetal Growth Retardation - epidemiology
Fetal Growth Retardation - etiology
Follow-Up Studies
Humans
Infant, Newborn
Mexico
Pre-Eclampsia - epidemiology
Pre-Eclampsia - etiology
Pregnancy
Pregnancy Complications - drug therapy
Pregnancy Outcome
Premature Birth - epidemiology
Premature Birth - etiology
Retrospective Studies
Stillbirth - epidemiology
title Maternal and fetal outcome in Mexican women with rheumatoid arthritis
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