Increased Radiosensitivity and the Basic Defect in Ataxia Telangiectasia

Summary Various cellular defects have been found in ataxia telangiectasia (A-T) cells including increased radiosensitivity, increased sensitivity to various chemical agents, a probable DNA repair defect and a defect in DNA synthesis. How these different features are related to each other is at prese...

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Veröffentlicht in:	International journal of radiation biology 1989, Vol.56 (5), p.677-684
Hauptverfasser:	Taylor, A.M.R., Metcalfe, J.A., McConville, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ataxia Telangiectasia - genetics Ataxia Telangiectasia - pathology Cell Survival - radiation effects Chromosome Aberrations Humans In Vitro Techniques Radiation Genetics Radiation Tolerance
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