Metabolism Study of Veratramine Associated with Neurotoxicity by Using HPLC-MSn

Veratramine (VAM) is the major lipid-soluble alkaloid existing in Veratrum nigrum L. that has been demonstrated to exert neurotoxic effects. To better understand the potential mechanism of neurotoxicity of VAM, VAM-induced DNA damage was measured in the cerebellum and cerebral cortex of mice after a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of chromatographic science 2015-08, Vol.53 (7), p.1092
Hauptverfasser:	Cong, Yue, Guo, Jinggong, Tang, Zhi, Lin, Shuhai, Zhang, Qingchun, Li, Jing, Cai, Zongwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - drug effects Brain - metabolism Chromatography, High Pressure Liquid - methods DNA Damage - drug effects Male Mice Microsomes, Liver - drug effects Microsomes, Liver - metabolism Rats Spectrometry, Mass, Electrospray Ionization - methods Veratrum - chemistry Veratrum Alkaloids - administration & dosage Veratrum Alkaloids - isolation & purification Veratrum Alkaloids - metabolism Veratrum Alkaloids - toxicity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!