Prognostic severity scores for patients with COPD exacerbations attending emergency departments
SETTING: Reported predictors of the adverse evolution of patients with chronic obstructive pulmonary disease exacerbations (eCOPD) are various and inconsistent in the bibliography.OBJECTIVE: To develop clinical prediction rules for short-term outcomes in eCOPD patients attending an emergency departm...
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| Veröffentlicht in: | The international journal of tuberculosis and lung disease 2014-12, Vol.18 (12), p.1415-1420 |
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| creator | Quintana, J. M. Esteban, C. Unzurrunzaga, A. Garcia-Gutierrez, S. Gonzalez, N. Lafuente, I. Bare, M. de Larrea, N. Fernandez Vidal, S. for the IRYSS-COPD Group |
| description | SETTING: Reported predictors of the adverse evolution of patients with chronic obstructive pulmonary disease exacerbations (eCOPD) are various and inconsistent in the bibliography.OBJECTIVE: To develop clinical prediction rules for short-term outcomes in eCOPD patients attending
an emergency department (ED).DESIGN: Prospective cohort study of patients with an eCOPD. Short-term outcomes were admission to an intensive care unit (ICU), admission to an intermediate respiratory care unit (IRCU) and death in these groups. Multivariate logistic regression models were
developed for each of the outcomes.RESULTS: Predictors of ICU or IRCU admission were use of long-term home oxygen therapy (LT-HOT) or non-invasive mechanical ventilation (NIMV), elevated PCO2 and decreased pH upon ED arrival (area under the curve [AUC] 0.87 in the derivation
sample; 0.89 in the validation sample). Among those admitted to an ICU or IRCU, predictors of death were increased age, use at home of LT-HOT or NIMV, use of inspiratory accessory muscles upon ED arrival and altered Glasgow Coma Scale ( |
| doi_str_mv | 10.5588/ijtld.14.0312 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_25517805</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ingid>iuatld/ijtld/2014/00000018/00000012/art00007</ingid><sourcerecordid>1639495211</sourcerecordid><originalsourceid>FETCH-LOGICAL-c458t-e8445a33f18ea34f1bd644348b41af26be54d24a5a1aa93b394c86fb298672de3</originalsourceid><addsrcrecordid>eNp1kU1v1DAQhiNERUvhyBX5gsQlW38mzhFt-ZIqtZXK2Zo4k8WrxFlsp7D8epzuLpzwxSP5mXfkZ4riDaMrpbS-cts0dCsmV1Qw_qy4YJqpsm44fZ5ryutS1Kw5L17GuKWUM8bqF8U5V4rVmqqLwtyFaeOnmJwlER8xuLQn0U4BI-mnQHaQHPoUyU-XvpP17d01wV9gMbT5YfKRQEroO-c3BEcMG_R2TzrcQUjj0veqOOthiPj6eF8W3z59fFh_KW9uP39df7gprVQ6lailVCBEzzSCkD1ru0pKIXUrGfS8alHJjktQwAAa0YpGWl31LW90VfMOxWXx_pC7C9OPGWMyo4sWhwE8TnM0rMotjcoCMloeUBumGAP2ZhfcCGFvGDWLU_Pk1DBpFqeZf3uMntsRu7_0SWIG3h0BiBaGPoC3Lv7jGkol1VXmrg9ctpXdgNlOc_DZinEzLBMPczldJj8dpk8FN9noUtU55v5_MfaUtGx-Wbx5ZNrnZp5XTzVX-VNKmw57mIdkEgSz-W1iLf4AFbiydA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1639495211</pqid></control><display><type>article</type><title>Prognostic severity scores for patients with COPD exacerbations attending emergency departments</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Quintana, J. M. ; Esteban, C. ; Unzurrunzaga, A. ; Garcia-Gutierrez, S. ; Gonzalez, N. ; Lafuente, I. ; Bare, M. ; de Larrea, N. Fernandez ; Vidal, S. ; for the IRYSS-COPD Group</creator><creatorcontrib>Quintana, J. M. ; Esteban, C. ; Unzurrunzaga, A. ; Garcia-Gutierrez, S. ; Gonzalez, N. ; Lafuente, I. ; Bare, M. ; de Larrea, N. Fernandez ; Vidal, S. ; for the IRYSS-COPD Group ; IRYSS-COPD Group ; for the IRYSS-COPD Group</creatorcontrib><description>SETTING: Reported predictors of the adverse evolution of patients with chronic obstructive pulmonary disease exacerbations (eCOPD) are various and inconsistent in the bibliography.OBJECTIVE: To develop clinical prediction rules for short-term outcomes in eCOPD patients attending
an emergency department (ED).DESIGN: Prospective cohort study of patients with an eCOPD. Short-term outcomes were admission to an intensive care unit (ICU), admission to an intermediate respiratory care unit (IRCU) and death in these groups. Multivariate logistic regression models were
developed for each of the outcomes.RESULTS: Predictors of ICU or IRCU admission were use of long-term home oxygen therapy (LT-HOT) or non-invasive mechanical ventilation (NIMV), elevated PCO2 and decreased pH upon ED arrival (area under the curve [AUC] 0.87 in the derivation
sample; 0.89 in the validation sample). Among those admitted to an ICU or IRCU, predictors of death were increased age, use at home of LT-HOT or NIMV, use of inspiratory accessory muscles upon ED arrival and altered Glasgow Coma Scale (<15 points) (AUC 0.78).CONCLUSIONS: Three clinical
predictors available in the ED can be used to create a simple score to predict the need for intensive treatment among eCOPD patients. Such a score can be a tool for clinical practice.</description><identifier>ISSN: 1027-3719</identifier><identifier>EISSN: 1815-7920</identifier><identifier>DOI: 10.5588/ijtld.14.0312</identifier><identifier>PMID: 25517805</identifier><language>eng</language><publisher>Paris: International Union Against Tuberculosis and Lung Disease</publisher><subject>Age Factors ; Aged ; Aged, 80 and over ; Area Under Curve ; Bacterial diseases ; Biological and medical sciences ; Chronic Obstructive Disease Progression ; Chronic obstructive pulmonary disease, asthma ; Cohort Studies ; Decision Support Techniques ; Disease Progression ; Emergency Service, Hospital ; Female ; Glasgow Coma Scale ; Hospital Mortality ; Human bacterial diseases ; Humans ; Infectious diseases ; Intensive Care Units ; Logistic Models ; Male ; Medical sciences ; Multivariate Analysis ; Odds Ratio ; Oxygen Inhalation Therapy - adverse effects ; Patient Admission ; Pneumology ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Pulmonary Disease ; Pulmonary Disease, Chronic Obstructive - diagnosis ; Pulmonary Disease, Chronic Obstructive - mortality ; Pulmonary Disease, Chronic Obstructive - physiopathology ; Pulmonary Disease, Chronic Obstructive - therapy ; Respiration, Artificial - adverse effects ; Risk Factors ; ROC Curve ; Severity Of Illness Index ; Spain ; Time Factors ; Tuberculosis and atypical mycobacterial infections</subject><ispartof>The international journal of tuberculosis and lung disease, 2014-12, Vol.18 (12), p.1415-1420</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c458t-e8445a33f18ea34f1bd644348b41af26be54d24a5a1aa93b394c86fb298672de3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=29004086$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25517805$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Quintana, J. M.</creatorcontrib><creatorcontrib>Esteban, C.</creatorcontrib><creatorcontrib>Unzurrunzaga, A.</creatorcontrib><creatorcontrib>Garcia-Gutierrez, S.</creatorcontrib><creatorcontrib>Gonzalez, N.</creatorcontrib><creatorcontrib>Lafuente, I.</creatorcontrib><creatorcontrib>Bare, M.</creatorcontrib><creatorcontrib>de Larrea, N. Fernandez</creatorcontrib><creatorcontrib>Vidal, S.</creatorcontrib><creatorcontrib>for the IRYSS-COPD Group</creatorcontrib><creatorcontrib>IRYSS-COPD Group</creatorcontrib><creatorcontrib>for the IRYSS-COPD Group</creatorcontrib><title>Prognostic severity scores for patients with COPD exacerbations attending emergency departments</title><title>The international journal of tuberculosis and lung disease</title><addtitle>Int J Tuberc Lung Dis</addtitle><description>SETTING: Reported predictors of the adverse evolution of patients with chronic obstructive pulmonary disease exacerbations (eCOPD) are various and inconsistent in the bibliography.OBJECTIVE: To develop clinical prediction rules for short-term outcomes in eCOPD patients attending
an emergency department (ED).DESIGN: Prospective cohort study of patients with an eCOPD. Short-term outcomes were admission to an intensive care unit (ICU), admission to an intermediate respiratory care unit (IRCU) and death in these groups. Multivariate logistic regression models were
developed for each of the outcomes.RESULTS: Predictors of ICU or IRCU admission were use of long-term home oxygen therapy (LT-HOT) or non-invasive mechanical ventilation (NIMV), elevated PCO2 and decreased pH upon ED arrival (area under the curve [AUC] 0.87 in the derivation
sample; 0.89 in the validation sample). Among those admitted to an ICU or IRCU, predictors of death were increased age, use at home of LT-HOT or NIMV, use of inspiratory accessory muscles upon ED arrival and altered Glasgow Coma Scale (<15 points) (AUC 0.78).CONCLUSIONS: Three clinical
predictors available in the ED can be used to create a simple score to predict the need for intensive treatment among eCOPD patients. Such a score can be a tool for clinical practice.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Area Under Curve</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Chronic Obstructive Disease Progression</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>Cohort Studies</subject><subject>Decision Support Techniques</subject><subject>Disease Progression</subject><subject>Emergency Service, Hospital</subject><subject>Female</subject><subject>Glasgow Coma Scale</subject><subject>Hospital Mortality</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Intensive Care Units</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Multivariate Analysis</subject><subject>Odds Ratio</subject><subject>Oxygen Inhalation Therapy - adverse effects</subject><subject>Patient Admission</subject><subject>Pneumology</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Pulmonary Disease</subject><subject>Pulmonary Disease, Chronic Obstructive - diagnosis</subject><subject>Pulmonary Disease, Chronic Obstructive - mortality</subject><subject>Pulmonary Disease, Chronic Obstructive - physiopathology</subject><subject>Pulmonary Disease, Chronic Obstructive - therapy</subject><subject>Respiration, Artificial - adverse effects</subject><subject>Risk Factors</subject><subject>ROC Curve</subject><subject>Severity Of Illness Index</subject><subject>Spain</subject><subject>Time Factors</subject><subject>Tuberculosis and atypical mycobacterial infections</subject><issn>1027-3719</issn><issn>1815-7920</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1v1DAQhiNERUvhyBX5gsQlW38mzhFt-ZIqtZXK2Zo4k8WrxFlsp7D8epzuLpzwxSP5mXfkZ4riDaMrpbS-cts0dCsmV1Qw_qy4YJqpsm44fZ5ryutS1Kw5L17GuKWUM8bqF8U5V4rVmqqLwtyFaeOnmJwlER8xuLQn0U4BI-mnQHaQHPoUyU-XvpP17d01wV9gMbT5YfKRQEroO-c3BEcMG_R2TzrcQUjj0veqOOthiPj6eF8W3z59fFh_KW9uP39df7gprVQ6lailVCBEzzSCkD1ru0pKIXUrGfS8alHJjktQwAAa0YpGWl31LW90VfMOxWXx_pC7C9OPGWMyo4sWhwE8TnM0rMotjcoCMloeUBumGAP2ZhfcCGFvGDWLU_Pk1DBpFqeZf3uMntsRu7_0SWIG3h0BiBaGPoC3Lv7jGkol1VXmrg9ctpXdgNlOc_DZinEzLBMPczldJj8dpk8FN9noUtU55v5_MfaUtGx-Wbx5ZNrnZp5XTzVX-VNKmw57mIdkEgSz-W1iLf4AFbiydA</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Quintana, J. M.</creator><creator>Esteban, C.</creator><creator>Unzurrunzaga, A.</creator><creator>Garcia-Gutierrez, S.</creator><creator>Gonzalez, N.</creator><creator>Lafuente, I.</creator><creator>Bare, M.</creator><creator>de Larrea, N. Fernandez</creator><creator>Vidal, S.</creator><creator>for the IRYSS-COPD Group</creator><general>International Union Against Tuberculosis and Lung Disease</general><general>International Union against Tuberculosis and Lung Disease</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141201</creationdate><title>Prognostic severity scores for patients with COPD exacerbations attending emergency departments</title><author>Quintana, J. M. ; Esteban, C. ; Unzurrunzaga, A. ; Garcia-Gutierrez, S. ; Gonzalez, N. ; Lafuente, I. ; Bare, M. ; de Larrea, N. Fernandez ; Vidal, S. ; for the IRYSS-COPD Group</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c458t-e8445a33f18ea34f1bd644348b41af26be54d24a5a1aa93b394c86fb298672de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Area Under Curve</topic><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Chronic Obstructive Disease Progression</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>Cohort Studies</topic><topic>Decision Support Techniques</topic><topic>Disease Progression</topic><topic>Emergency Service, Hospital</topic><topic>Female</topic><topic>Glasgow Coma Scale</topic><topic>Hospital Mortality</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Intensive Care Units</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Multivariate Analysis</topic><topic>Odds Ratio</topic><topic>Oxygen Inhalation Therapy - adverse effects</topic><topic>Patient Admission</topic><topic>Pneumology</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Pulmonary Disease</topic><topic>Pulmonary Disease, Chronic Obstructive - diagnosis</topic><topic>Pulmonary Disease, Chronic Obstructive - mortality</topic><topic>Pulmonary Disease, Chronic Obstructive - physiopathology</topic><topic>Pulmonary Disease, Chronic Obstructive - therapy</topic><topic>Respiration, Artificial - adverse effects</topic><topic>Risk Factors</topic><topic>ROC Curve</topic><topic>Severity Of Illness Index</topic><topic>Spain</topic><topic>Time Factors</topic><topic>Tuberculosis and atypical mycobacterial infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Quintana, J. M.</creatorcontrib><creatorcontrib>Esteban, C.</creatorcontrib><creatorcontrib>Unzurrunzaga, A.</creatorcontrib><creatorcontrib>Garcia-Gutierrez, S.</creatorcontrib><creatorcontrib>Gonzalez, N.</creatorcontrib><creatorcontrib>Lafuente, I.</creatorcontrib><creatorcontrib>Bare, M.</creatorcontrib><creatorcontrib>de Larrea, N. Fernandez</creatorcontrib><creatorcontrib>Vidal, S.</creatorcontrib><creatorcontrib>for the IRYSS-COPD Group</creatorcontrib><creatorcontrib>IRYSS-COPD Group</creatorcontrib><creatorcontrib>for the IRYSS-COPD Group</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The international journal of tuberculosis and lung disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Quintana, J. M.</au><au>Esteban, C.</au><au>Unzurrunzaga, A.</au><au>Garcia-Gutierrez, S.</au><au>Gonzalez, N.</au><au>Lafuente, I.</au><au>Bare, M.</au><au>de Larrea, N. Fernandez</au><au>Vidal, S.</au><au>for the IRYSS-COPD Group</au><aucorp>IRYSS-COPD Group</aucorp><aucorp>for the IRYSS-COPD Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic severity scores for patients with COPD exacerbations attending emergency departments</atitle><jtitle>The international journal of tuberculosis and lung disease</jtitle><addtitle>Int J Tuberc Lung Dis</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>18</volume><issue>12</issue><spage>1415</spage><epage>1420</epage><pages>1415-1420</pages><issn>1027-3719</issn><eissn>1815-7920</eissn><abstract>SETTING: Reported predictors of the adverse evolution of patients with chronic obstructive pulmonary disease exacerbations (eCOPD) are various and inconsistent in the bibliography.OBJECTIVE: To develop clinical prediction rules for short-term outcomes in eCOPD patients attending
an emergency department (ED).DESIGN: Prospective cohort study of patients with an eCOPD. Short-term outcomes were admission to an intensive care unit (ICU), admission to an intermediate respiratory care unit (IRCU) and death in these groups. Multivariate logistic regression models were
developed for each of the outcomes.RESULTS: Predictors of ICU or IRCU admission were use of long-term home oxygen therapy (LT-HOT) or non-invasive mechanical ventilation (NIMV), elevated PCO2 and decreased pH upon ED arrival (area under the curve [AUC] 0.87 in the derivation
sample; 0.89 in the validation sample). Among those admitted to an ICU or IRCU, predictors of death were increased age, use at home of LT-HOT or NIMV, use of inspiratory accessory muscles upon ED arrival and altered Glasgow Coma Scale (<15 points) (AUC 0.78).CONCLUSIONS: Three clinical
predictors available in the ED can be used to create a simple score to predict the need for intensive treatment among eCOPD patients. Such a score can be a tool for clinical practice.</abstract><cop>Paris</cop><pub>International Union Against Tuberculosis and Lung Disease</pub><pmid>25517805</pmid><doi>10.5588/ijtld.14.0312</doi><tpages>6</tpages></addata></record> |
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| subjects | Age Factors Aged Aged, 80 and over Area Under Curve Bacterial diseases Biological and medical sciences Chronic Obstructive Disease Progression Chronic obstructive pulmonary disease, asthma Cohort Studies Decision Support Techniques Disease Progression Emergency Service, Hospital Female Glasgow Coma Scale Hospital Mortality Human bacterial diseases Humans Infectious diseases Intensive Care Units Logistic Models Male Medical sciences Multivariate Analysis Odds Ratio Oxygen Inhalation Therapy - adverse effects Patient Admission Pneumology Predictive Value of Tests Prognosis Prospective Studies Pulmonary Disease Pulmonary Disease, Chronic Obstructive - diagnosis Pulmonary Disease, Chronic Obstructive - mortality Pulmonary Disease, Chronic Obstructive - physiopathology Pulmonary Disease, Chronic Obstructive - therapy Respiration, Artificial - adverse effects Risk Factors ROC Curve Severity Of Illness Index Spain Time Factors Tuberculosis and atypical mycobacterial infections |
| title | Prognostic severity scores for patients with COPD exacerbations attending emergency departments |
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