Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion

Coordinated cell proliferation and ability to form intercellular seals are essential features of epithelial tissue function. Tight junctions (TJs) classically act as paracellular diffusion barriers. More recently, their role in regulating epithelial cell proliferation in conjunction with scaffolding...

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Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2014-10, Vol.13 (19), p.3059-3075
Hauptverfasser:	Qiao, Xiaomu, Roth, Isabelle, Féraille, Eric, Hasler, Udo
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion Animals Cell Adhesion cell cycle Cell Cycle Checkpoints Cell Proliferation Cells, Cultured cyclin D1 Cyclin D1 - metabolism Cyclin-Dependent Kinase Inhibitor p21 - metabolism kidney collecting duct Kidney Tubules, Collecting - cytology Kidney Tubules, Collecting - metabolism Proliferating Cell Nuclear Antigen - metabolism proliferation Rats Rats, Sprague-Dawley RNA Interference RNA, Messenger - metabolism RNA, Small Interfering - metabolism ZONAB zonula occludens Zonula Occludens Proteins - antagonists & inhibitors Zonula Occludens Proteins - genetics Zonula Occludens Proteins - metabolism Zonula Occludens-1 Protein - antagonists & inhibitors Zonula Occludens-1 Protein - genetics Zonula Occludens-1 Protein - metabolism Zonula Occludens-2 Protein - antagonists & inhibitors Zonula Occludens-2 Protein - genetics Zonula Occludens-2 Protein - metabolism
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