Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization
The stimuli-responsive polypeptides have drawn extensive attention because of their promising applications in biotechnology considering their biocompatibility, biodegradability, and bioactivity. In this tutorial review, we summarize the most recent progress in this area, including thermo-, redox-, p...
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| Veröffentlicht in: | Chemical Society reviews 2015-01, Vol.44 (3), p.612-622 |
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| creator | Shen, Yong Fu, Xiaohui Fu, Wenxin Li, Zhibo |
| description | The stimuli-responsive polypeptides have drawn extensive attention because of their promising applications in biotechnology considering their biocompatibility, biodegradability, and bioactivity. In this tutorial review, we summarize the most recent progress in this area, including thermo-, redox-, photo-, and biomolecule responsive polypeptides over the past decade. The design and synthesis of stimuli-responsive polypeptides will be briefly introduced. The correlation between the structure and properties, particularly the effects of polypeptide conformation, will be emphasized here. In addition, the applications of stimuli-responsive polypeptides in controlled drug release and tissue engineering are briefly discussed.
This tutorial review summarizes the most recent progress in stimuli-responsive polypeptides over the past decade. |
| doi_str_mv | 10.1039/c4cs00271g |
| format | Article |
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| ispartof | Chemical Society reviews, 2015-01, Vol.44 (3), p.612-622 |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Biochemistry Biodegradability Biotechnology Correlation Drug delivery systems Models, Molecular Peptides Polymers Polypeptides Synthesis Temperature Tissue engineering |
| title | Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization |
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