Human cytomegalovirus and Epstein-Barr virus infection impact on (18)F-FDG PET/CT SUVmax, CT volumetric and KRAS-based parameters of patients with locally advanced rectal cancer treated with neoadjuvant therapy

It has long been debated whether human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) are associated with rectal cancer. The gene products of HCMV and EBV contribute to cell-cycle progression, mutagenesis, angiogenesis and immune evasion. The aim of this prospective study was to analyse the ass...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2015-02, Vol.42 (2), p.186
Hauptverfasser:	Sole, Claudio V, Calvo, Felipe A, Ferrer, Carlos, Alvarez, Emilio, Carreras, Jose L, Ochoa, Enrique
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Chemoradiotherapy Cytomegalovirus Infections - complications Cytomegalovirus Infections - diagnostic imaging Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - diagnostic imaging Female Fluorodeoxyglucose F18 - pharmacokinetics Humans Male Middle Aged Multimodal Imaging Neoadjuvant Therapy Positron-Emission Tomography Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins p21(ras) Radiopharmaceuticals - pharmacokinetics ras Proteins - genetics Rectal Neoplasms - complications Rectal Neoplasms - diagnostic imaging Rectal Neoplasms - genetics Rectal Neoplasms - therapy Tomography, X-Ray Computed
Online-Zugang:	Volltext
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