Vaccines as an agent for immunization against HPV

Considered a highly prevalent infection throughout the world, the human papillomavirus (HPV) is a DNA virus that infects the genital mucosa and has high carcinogenic potential, being related to an increased risk of lower genital tract lesions, such as cervical cancer. This cancer is responsible for...

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Veröffentlicht in:Ciência & saude coletiva 2014-09, Vol.19 (9), p.3799
Hauptverfasser: Zardo, Geisa Picksius, Farah, Flávia Peixoto, Mendes, Fernanda Gabriela, Franco, Camila Ament Giuliani Dos Santos, Molina, Giseli Vieira Machado, Melo, Gislaine Nochetti de, Kusma, Solena Ziemer
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container_issue 9
container_start_page 3799
container_title Ciência & saude coletiva
container_volume 19
creator Zardo, Geisa Picksius
Farah, Flávia Peixoto
Mendes, Fernanda Gabriela
Franco, Camila Ament Giuliani Dos Santos
Molina, Giseli Vieira Machado
Melo, Gislaine Nochetti de
Kusma, Solena Ziemer
description Considered a highly prevalent infection throughout the world, the human papillomavirus (HPV) is a DNA virus that infects the genital mucosa and has high carcinogenic potential, being related to an increased risk of lower genital tract lesions, such as cervical cancer. This cancer is responsible for the deaths of about 231,000 women per year worldwide, which means that HPV is a major problem for public health. Knowing that the most effective and cost-effective way to control an infectious disease is the development of vaccines, two prophylactic vaccines have been developed and approved in Brazil, one of which is bivalent and the other is tetravalent. This review of the literature seeks to present the characteristics of the HPV virus, types of vaccines available on the market, their indications and contraindications, their adverse effects, their effectiveness, their geometric mean titer (GMT) and their cost-effectiveness.
doi_str_mv 10.1590/1413-81232014199.01532013
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subjects Contraindications
Cost-Benefit Analysis
Female
Health Policy
Humans
Papillomavirus Infections - complications
Papillomavirus Infections - prevention & control
Papillomavirus Vaccines - economics
Papillomavirus Vaccines - immunology
Uterine Cervical Neoplasms - prevention & control
Uterine Cervical Neoplasms - virology
title Vaccines as an agent for immunization against HPV
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