Alcohol use disorders and current pharmacological therapies: the role of GABA(A) receptors

Alcohol use disorders (AUD) are defined as alcohol abuse and alcohol dependence, which create large problems both for society and for the drinkers themselves. To date, no therapeutic can effectively solve these problems. Understanding the underlying mechanisms leading to AUD is critically important...

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Veröffentlicht in:	Acta pharmacologica Sinica 2014-08, Vol.35 (8), p.981
Hauptverfasser:	Liang, Jing, Olsen, Richard W
Format:	Artikel
Sprache:	eng
Schlagworte:	Acamprosate Alcohol Deterrents - pharmacology Alcohol Deterrents - therapeutic use Alcohol Drinking - adverse effects Alcohol Drinking - metabolism Alcoholism - drug therapy Alcoholism - metabolism Animals Benzodiazepines - pharmacology Benzodiazepines - therapeutic use Disulfiram - pharmacology Disulfiram - therapeutic use Ethanol - adverse effects Ethanol - metabolism Fructose - analogs & derivatives Fructose - pharmacology Fructose - therapeutic use Humans Naltrexone - pharmacology Naltrexone - therapeutic use Narcotic Antagonists - pharmacology Narcotic Antagonists - therapeutic use Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Plant Preparations - pharmacology Plant Preparations - therapeutic use Receptors, GABA-A - metabolism Taurine - analogs & derivatives Taurine - pharmacology Taurine - therapeutic use Topiramate
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