Bio-functional pickles that reduce blood pressure of rats
Addition of γ-aminobutyric acid (GABA) and angiotensin converting enzyme (ACE)-inhibitory peptides to the pickles was studied in order to develop a new type of pickles that reduce blood pressure. Based on the outcome of these studies, a new type of fermentation bed composed of rice bran and white mi...
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| Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2014, Vol.78 (5), p.882-890 |
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| container_title | Bioscience, biotechnology, and biochemistry |
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| creator | Oda, Kohei Imanishi, Takanori Yamane, Yoshito Ueno, Yoshie Mori, Yoshiharu |
| description | Addition of γ-aminobutyric acid (GABA) and angiotensin converting enzyme (ACE)-inhibitory peptides to the pickles was studied in order to develop a new type of pickles that reduce blood pressure. Based on the outcome of these studies, a new type of fermentation bed composed of rice bran and white miso has been successfully developed. The advantage of such pickles is that they not only contain both GABA and ACE-inhibitory peptides, but also that their taste and flavor are excellent, with colors close to the original ones. The new type of pickles could temporarily reduce blood pressure in two types of rats, spontaneously hypertensive rats and NaCl-sensitive model rats. Thus, the newly developed pickles appear to be beneficial for pickle business.
The newly developed pickles with GABA and ACE-inhibitory peptides could temporarily reduce blood pressure of hypertensive rats, which is beneficial for pickle business. |
| doi_str_mv | 10.1080/09168451.2014.893187 |
| format | Article |
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The newly developed pickles with GABA and ACE-inhibitory peptides could temporarily reduce blood pressure of hypertensive rats, which is beneficial for pickle business.</description><identifier>ISSN: 0916-8451</identifier><identifier>EISSN: 1347-6947</identifier><identifier>DOI: 10.1080/09168451.2014.893187</identifier><identifier>PMID: 25035994</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Administration, Oral ; angiotensin converting enzyme (ACE)-inhibitory peptides ; Angiotensin-Converting Enzyme Inhibitors - analysis ; Animals ; anti-hypertensive effects ; Antihypertensive Agents - administration & dosage ; Antihypertensive Agents - chemistry ; Antihypertensive Agents - pharmacology ; Blood Pressure - drug effects ; Color ; Fermentation ; Food Handling ; Food, Fortified ; gamma-Aminobutyric Acid - analysis ; Male ; Oryza ; pickles ; Rats ; Rats, Inbred SHR ; Sodium Chloride - pharmacology ; Soy Foods ; spontaneously hypertensive rats ; Taste ; γ-aminobutyric acid (GABA)</subject><ispartof>Bioscience, biotechnology, and biochemistry, 2014, Vol.78 (5), p.882-890</ispartof><rights>2014 Japan Society for Bioscience, Biotechnology, and Agrochemistry 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c427t-be215f873136a578fa00f36cb7056f1d6715fa0f2df189e080fbde5027e415903</citedby><cites>FETCH-LOGICAL-c427t-be215f873136a578fa00f36cb7056f1d6715fa0f2df189e080fbde5027e415903</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25035994$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Oda, Kohei</creatorcontrib><creatorcontrib>Imanishi, Takanori</creatorcontrib><creatorcontrib>Yamane, Yoshito</creatorcontrib><creatorcontrib>Ueno, Yoshie</creatorcontrib><creatorcontrib>Mori, Yoshiharu</creatorcontrib><title>Bio-functional pickles that reduce blood pressure of rats</title><title>Bioscience, biotechnology, and biochemistry</title><addtitle>Biosci Biotechnol Biochem</addtitle><description>Addition of γ-aminobutyric acid (GABA) and angiotensin converting enzyme (ACE)-inhibitory peptides to the pickles was studied in order to develop a new type of pickles that reduce blood pressure. Based on the outcome of these studies, a new type of fermentation bed composed of rice bran and white miso has been successfully developed. The advantage of such pickles is that they not only contain both GABA and ACE-inhibitory peptides, but also that their taste and flavor are excellent, with colors close to the original ones. The new type of pickles could temporarily reduce blood pressure in two types of rats, spontaneously hypertensive rats and NaCl-sensitive model rats. Thus, the newly developed pickles appear to be beneficial for pickle business.
The newly developed pickles with GABA and ACE-inhibitory peptides could temporarily reduce blood pressure of hypertensive rats, which is beneficial for pickle business.</description><subject>Administration, Oral</subject><subject>angiotensin converting enzyme (ACE)-inhibitory peptides</subject><subject>Angiotensin-Converting Enzyme Inhibitors - analysis</subject><subject>Animals</subject><subject>anti-hypertensive effects</subject><subject>Antihypertensive Agents - administration & dosage</subject><subject>Antihypertensive Agents - chemistry</subject><subject>Antihypertensive Agents - pharmacology</subject><subject>Blood Pressure - drug effects</subject><subject>Color</subject><subject>Fermentation</subject><subject>Food Handling</subject><subject>Food, Fortified</subject><subject>gamma-Aminobutyric Acid - analysis</subject><subject>Male</subject><subject>Oryza</subject><subject>pickles</subject><subject>Rats</subject><subject>Rats, Inbred SHR</subject><subject>Sodium Chloride - pharmacology</subject><subject>Soy Foods</subject><subject>spontaneously hypertensive rats</subject><subject>Taste</subject><subject>γ-aminobutyric acid (GABA)</subject><issn>0916-8451</issn><issn>1347-6947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1LxDAURYMozjj6D0S6dNNO0nw1K9HBLxhwo-uQpglW06YmLTL_3pbOuBRXgZdz7-MdAC4RzBAs4BoKxApCUZZDRLJCYFTwI7BEmPCUCcKPwXJC0olZgLMYPyAcBxSdgkVOIaZCkCUQd7VP7dDqvvatcklX609nYtK_qz4Jphq0SUrnfZV0wcQ4BJN4mwTVx3NwYpWL5mL_rsDbw_3r5indvjw-b263qSY579PS5IjagmOEmaK8sApCi5kuOaTMoorx8VtBm1cWFcKMl9myMhTm3BBEBcQrcD33dsF_DSb2sqmjNs6p1vghSkQJy8dyJkaUzKgOPsZgrOxC3aiwkwjKSZo8SJOTNDlLG2NX-w1D2ZjqN3SwNALrGfBD99_KmzlRt9aHRn374CrZq53zwQbV6jpK_GfDD2tCh2c</recordid><startdate>2014</startdate><enddate>2014</enddate><creator>Oda, Kohei</creator><creator>Imanishi, Takanori</creator><creator>Yamane, Yoshito</creator><creator>Ueno, Yoshie</creator><creator>Mori, Yoshiharu</creator><general>Taylor & Francis</general><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2014</creationdate><title>Bio-functional pickles that reduce blood pressure of rats</title><author>Oda, Kohei ; 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Based on the outcome of these studies, a new type of fermentation bed composed of rice bran and white miso has been successfully developed. The advantage of such pickles is that they not only contain both GABA and ACE-inhibitory peptides, but also that their taste and flavor are excellent, with colors close to the original ones. The new type of pickles could temporarily reduce blood pressure in two types of rats, spontaneously hypertensive rats and NaCl-sensitive model rats. Thus, the newly developed pickles appear to be beneficial for pickle business.
The newly developed pickles with GABA and ACE-inhibitory peptides could temporarily reduce blood pressure of hypertensive rats, which is beneficial for pickle business.</abstract><cop>England</cop><pub>Taylor & Francis</pub><pmid>25035994</pmid><doi>10.1080/09168451.2014.893187</doi><tpages>9</tpages></addata></record> |
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| ispartof | Bioscience, biotechnology, and biochemistry, 2014, Vol.78 (5), p.882-890 |
| issn | 0916-8451 1347-6947 |
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| recordid | cdi_pubmed_primary_25035994 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Freely Accessible Japanese Titles; EZB-FREE-00999 freely available EZB journals |
| subjects | Administration, Oral angiotensin converting enzyme (ACE)-inhibitory peptides Angiotensin-Converting Enzyme Inhibitors - analysis Animals anti-hypertensive effects Antihypertensive Agents - administration & dosage Antihypertensive Agents - chemistry Antihypertensive Agents - pharmacology Blood Pressure - drug effects Color Fermentation Food Handling Food, Fortified gamma-Aminobutyric Acid - analysis Male Oryza pickles Rats Rats, Inbred SHR Sodium Chloride - pharmacology Soy Foods spontaneously hypertensive rats Taste γ-aminobutyric acid (GABA) |
| title | Bio-functional pickles that reduce blood pressure of rats |
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