Identification of a selenocysteyl-tRNA(Ser) in mammalian cells that recognizes the nonsense codon, UGA

The presence of a unique opal suppressor seryl-tRNA in higher vertebrates which is converted to phosphoseryl-tRNA has been known for several years, but its function has been uncertain (see Hatfield, D. (1985) Trends Biochem. Sci. 10, 201-204 for review). In the present study, we demonstrate that thi...

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Veröffentlicht in:	The Journal of biological chemistry 1989-06, Vol.264 (17), p.9724
Hauptverfasser:	Lee, B J, Worland, P J, Davis, J N, Stadtman, T C, Hatfield, D L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Cell Line Codon Mammary Neoplasms, Experimental - metabolism Rats Ribosomes - metabolism RNA, Messenger RNA, Transfer, Amino Acyl - genetics RNA, Transfer, Amino Acyl - isolation & purification RNA, Transfer, Amino Acyl - metabolism RNA, Transfer, Ser - genetics RNA, Transfer, Ser - metabolism Selenious Acid Selenium - metabolism Selenium Radioisotopes Serine - metabolism Tritium
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