Anesthetic interactions of midazolam and fentanyl: is there acute tolerance to the opioid?

The anesthetic effects and interactions of midazolam and fentanyl were determined in terms of their reduction of enflurane MAC in dogs, and the effects of their specific antagonists were also investigated. Control enflurane MAC was determined by the tail clamp method in 18 mongrel dogs. Each animal...

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Veröffentlicht in:Anesthesiology (Philadelphia) 1989-04, Vol.70 (4), p.667-671
Hauptverfasser: SCHWIEGER, I. M, HALL, R. I, SZIAM, F, HUG, C. C. JR
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Sprache:eng
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