Advanced demodulation technique for the extraction of tissue optical properties and structural orientation contrast in the spatial frequency domain
We have developed a method for extracting spatial frequency information content from biological tissue, which is used to calculate tissue optical properties and determine tissue structural orientation. This demodulation method employs a two-dimensional Hilbert transform using a spiral phase function...
Gespeichert in:
| Veröffentlicht in: | Journal of biomedical optics 2014-05, Vol.19 (5), p.056013-056013 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 056013 |
|---|---|
| container_issue | 5 |
| container_start_page | 056013 |
| container_title | Journal of biomedical optics |
| container_volume | 19 |
| creator | Nadeau, Kyle P Durkin, Anthony J Tromberg, Bruce J |
| description | We have developed a method for extracting spatial frequency information content from biological tissue, which is used to calculate tissue optical properties and determine tissue structural orientation. This demodulation method employs a two-dimensional Hilbert transform using a spiral phase function in Fourier space. The approach presented here allows for the determination of tissue optical properties using a single frame of data for each modulation frequency, increasing imaging speed by two to threefold versus conventional, three-phase spatial frequency domain imaging (SFDI). This new single-phase Hilbert transform approach recovers optical property and scattering orientation index values within 1% and 10% of three-phase SFDI, respectively. These results suggest that, using the Hilbert demodulation technique, SFDI data acquisition speed can be increased significantly while preserving data quality, which will help us move forward toward the implementation of a real-time SFDI platform. |
| doi_str_mv | 10.1117/1.JBO.19.5.056013 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_24858131</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1529844261</sourcerecordid><originalsourceid>FETCH-LOGICAL-c616t-e341a28ca50eed9307a6813f1b0c8400399786004df309295e3a4aaf53c0ad483</originalsourceid><addsrcrecordid>eNqFkc1u1DAUhSMEomXgAdggL9kk-MaOx94gDYXyo0plAWwt17lhXGXsYDsV5TV4YdxJKf9iY1v3HH--16eqHgJtAGD9BJo3z04bUE3X0E5QYLeqQyiHum0l3C5nKlnNhJAH1b2UzimlUihxtzpouewkMDisvm76C-Mt9qTHXejn0WQXPMlot959mpEMIZK8RYKfczR2L4aBZJdSEcOUnTUjmWKYMGaHiRjfk5TjbPMcixKiQ58XqA2-MFImzu-RaSr14hkilpe8vSR92Bnn71d3BjMmfHC9r6r3xy_eHb2qT05fvj7anNRWgMg1Mg6mldZ0FLFXjK6NKEMNcEat5JQypdZSUMr7gVHVqg6Z4cYMHbPU9FyyVfV04U7z2Q57i1ftjXqKbmfipQ7G6V8V77b6Y7jQnDLgbF0Aj68BMZQJUtY7lyyOo_EY5qRBdMBpy1X3f2vXKsl5K6BYYbHaGFKKONx0BFRf5a5Bl9w1KN3pJfdy59HPo9zc-B50MXxYDGlyqM_DHH352h-cL24q62_YfXVTcrUjvn1-_Ic8lZ9dVc3fwP9u9RujktfG</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1529844261</pqid></control><display><type>article</type><title>Advanced demodulation technique for the extraction of tissue optical properties and structural orientation contrast in the spatial frequency domain</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Nadeau, Kyle P ; Durkin, Anthony J ; Tromberg, Bruce J</creator><creatorcontrib>Nadeau, Kyle P ; Durkin, Anthony J ; Tromberg, Bruce J</creatorcontrib><description>We have developed a method for extracting spatial frequency information content from biological tissue, which is used to calculate tissue optical properties and determine tissue structural orientation. This demodulation method employs a two-dimensional Hilbert transform using a spiral phase function in Fourier space. The approach presented here allows for the determination of tissue optical properties using a single frame of data for each modulation frequency, increasing imaging speed by two to threefold versus conventional, three-phase spatial frequency domain imaging (SFDI). This new single-phase Hilbert transform approach recovers optical property and scattering orientation index values within 1% and 10% of three-phase SFDI, respectively. These results suggest that, using the Hilbert demodulation technique, SFDI data acquisition speed can be increased significantly while preserving data quality, which will help us move forward toward the implementation of a real-time SFDI platform.</description><identifier>ISSN: 1083-3668</identifier><identifier>EISSN: 1560-2281</identifier><identifier>DOI: 10.1117/1.JBO.19.5.056013</identifier><identifier>PMID: 24858131</identifier><language>eng</language><publisher>United States: Society of Photo-Optical Instrumentation Engineers</publisher><subject>Algorithms ; Computer Simulation ; Demodulation ; Forearm - physiology ; Fourier Analysis ; Frequency domains ; Humans ; Image Processing, Computer-Assisted - methods ; Imaging ; Modulation ; Optical Imaging - methods ; Optical properties ; Orientation ; Phantoms, Imaging ; Research Papers: Imaging ; Spectrum Analysis - methods ; Spirals ; Transforms</subject><ispartof>Journal of biomedical optics, 2014-05, Vol.19 (5), p.056013-056013</ispartof><rights>2014 Society of Photo-Optical Instrumentation Engineers (SPIE)</rights><rights>2014 Society of Photo-Optical Instrumentation Engineers (SPIE) 2014 Society of Photo-Optical Instrumentation Engineers</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c616t-e341a28ca50eed9307a6813f1b0c8400399786004df309295e3a4aaf53c0ad483</citedby><cites>FETCH-LOGICAL-c616t-e341a28ca50eed9307a6813f1b0c8400399786004df309295e3a4aaf53c0ad483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031437/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031437/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24858131$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nadeau, Kyle P</creatorcontrib><creatorcontrib>Durkin, Anthony J</creatorcontrib><creatorcontrib>Tromberg, Bruce J</creatorcontrib><title>Advanced demodulation technique for the extraction of tissue optical properties and structural orientation contrast in the spatial frequency domain</title><title>Journal of biomedical optics</title><addtitle>J. Biomed. Opt</addtitle><description>We have developed a method for extracting spatial frequency information content from biological tissue, which is used to calculate tissue optical properties and determine tissue structural orientation. This demodulation method employs a two-dimensional Hilbert transform using a spiral phase function in Fourier space. The approach presented here allows for the determination of tissue optical properties using a single frame of data for each modulation frequency, increasing imaging speed by two to threefold versus conventional, three-phase spatial frequency domain imaging (SFDI). This new single-phase Hilbert transform approach recovers optical property and scattering orientation index values within 1% and 10% of three-phase SFDI, respectively. These results suggest that, using the Hilbert demodulation technique, SFDI data acquisition speed can be increased significantly while preserving data quality, which will help us move forward toward the implementation of a real-time SFDI platform.</description><subject>Algorithms</subject><subject>Computer Simulation</subject><subject>Demodulation</subject><subject>Forearm - physiology</subject><subject>Fourier Analysis</subject><subject>Frequency domains</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - methods</subject><subject>Imaging</subject><subject>Modulation</subject><subject>Optical Imaging - methods</subject><subject>Optical properties</subject><subject>Orientation</subject><subject>Phantoms, Imaging</subject><subject>Research Papers: Imaging</subject><subject>Spectrum Analysis - methods</subject><subject>Spirals</subject><subject>Transforms</subject><issn>1083-3668</issn><issn>1560-2281</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAUhSMEomXgAdggL9kk-MaOx94gDYXyo0plAWwt17lhXGXsYDsV5TV4YdxJKf9iY1v3HH--16eqHgJtAGD9BJo3z04bUE3X0E5QYLeqQyiHum0l3C5nKlnNhJAH1b2UzimlUihxtzpouewkMDisvm76C-Mt9qTHXejn0WQXPMlot959mpEMIZK8RYKfczR2L4aBZJdSEcOUnTUjmWKYMGaHiRjfk5TjbPMcixKiQ58XqA2-MFImzu-RaSr14hkilpe8vSR92Bnn71d3BjMmfHC9r6r3xy_eHb2qT05fvj7anNRWgMg1Mg6mldZ0FLFXjK6NKEMNcEat5JQypdZSUMr7gVHVqg6Z4cYMHbPU9FyyVfV04U7z2Q57i1ftjXqKbmfipQ7G6V8V77b6Y7jQnDLgbF0Aj68BMZQJUtY7lyyOo_EY5qRBdMBpy1X3f2vXKsl5K6BYYbHaGFKKONx0BFRf5a5Bl9w1KN3pJfdy59HPo9zc-B50MXxYDGlyqM_DHH352h-cL24q62_YfXVTcrUjvn1-_Ic8lZ9dVc3fwP9u9RujktfG</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>Nadeau, Kyle P</creator><creator>Durkin, Anthony J</creator><creator>Tromberg, Bruce J</creator><general>Society of Photo-Optical Instrumentation Engineers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>L7M</scope><scope>5PM</scope></search><sort><creationdate>20140501</creationdate><title>Advanced demodulation technique for the extraction of tissue optical properties and structural orientation contrast in the spatial frequency domain</title><author>Nadeau, Kyle P ; Durkin, Anthony J ; Tromberg, Bruce J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c616t-e341a28ca50eed9307a6813f1b0c8400399786004df309295e3a4aaf53c0ad483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Algorithms</topic><topic>Computer Simulation</topic><topic>Demodulation</topic><topic>Forearm - physiology</topic><topic>Fourier Analysis</topic><topic>Frequency domains</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted - methods</topic><topic>Imaging</topic><topic>Modulation</topic><topic>Optical Imaging - methods</topic><topic>Optical properties</topic><topic>Orientation</topic><topic>Phantoms, Imaging</topic><topic>Research Papers: Imaging</topic><topic>Spectrum Analysis - methods</topic><topic>Spirals</topic><topic>Transforms</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nadeau, Kyle P</creatorcontrib><creatorcontrib>Durkin, Anthony J</creatorcontrib><creatorcontrib>Tromberg, Bruce J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of biomedical optics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nadeau, Kyle P</au><au>Durkin, Anthony J</au><au>Tromberg, Bruce J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Advanced demodulation technique for the extraction of tissue optical properties and structural orientation contrast in the spatial frequency domain</atitle><jtitle>Journal of biomedical optics</jtitle><addtitle>J. Biomed. Opt</addtitle><date>2014-05-01</date><risdate>2014</risdate><volume>19</volume><issue>5</issue><spage>056013</spage><epage>056013</epage><pages>056013-056013</pages><issn>1083-3668</issn><eissn>1560-2281</eissn><abstract>We have developed a method for extracting spatial frequency information content from biological tissue, which is used to calculate tissue optical properties and determine tissue structural orientation. This demodulation method employs a two-dimensional Hilbert transform using a spiral phase function in Fourier space. The approach presented here allows for the determination of tissue optical properties using a single frame of data for each modulation frequency, increasing imaging speed by two to threefold versus conventional, three-phase spatial frequency domain imaging (SFDI). This new single-phase Hilbert transform approach recovers optical property and scattering orientation index values within 1% and 10% of three-phase SFDI, respectively. These results suggest that, using the Hilbert demodulation technique, SFDI data acquisition speed can be increased significantly while preserving data quality, which will help us move forward toward the implementation of a real-time SFDI platform.</abstract><cop>United States</cop><pub>Society of Photo-Optical Instrumentation Engineers</pub><pmid>24858131</pmid><doi>10.1117/1.JBO.19.5.056013</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1083-3668 |
| ispartof | Journal of biomedical optics, 2014-05, Vol.19 (5), p.056013-056013 |
| issn | 1083-3668 1560-2281 |
| language | eng |
| recordid | cdi_pubmed_primary_24858131 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Algorithms Computer Simulation Demodulation Forearm - physiology Fourier Analysis Frequency domains Humans Image Processing, Computer-Assisted - methods Imaging Modulation Optical Imaging - methods Optical properties Orientation Phantoms, Imaging Research Papers: Imaging Spectrum Analysis - methods Spirals Transforms |
| title | Advanced demodulation technique for the extraction of tissue optical properties and structural orientation contrast in the spatial frequency domain |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T15%3A00%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Advanced%20demodulation%20technique%20for%20the%20extraction%20of%20tissue%20optical%20properties%20and%20structural%20orientation%20contrast%20in%20the%20spatial%20frequency%20domain&rft.jtitle=Journal%20of%20biomedical%20optics&rft.au=Nadeau,%20Kyle%20P&rft.date=2014-05-01&rft.volume=19&rft.issue=5&rft.spage=056013&rft.epage=056013&rft.pages=056013-056013&rft.issn=1083-3668&rft.eissn=1560-2281&rft_id=info:doi/10.1117/1.JBO.19.5.056013&rft_dat=%3Cproquest_pubme%3E1529844261%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1529844261&rft_id=info:pmid/24858131&rfr_iscdi=true |