Expression of Glutamine Transporter Slc38a3 (SNAT3) During Acidosis is Mediated by a Different Mechanism than Tissue-Specific Expression

Background: Despite homeostatic pH regulation, systemic and cellular pH changes take place and strongly influence metabolic processes. Transcription of the glutamine transporter SNAT3 (Slc38a3) for instance is highly up-regulated in the kidney during metabolic acidosis to provide glutamine for ammon...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cellular physiology and biochemistry 2014-01, Vol.33 (5), p.1591-1606
Hauptverfasser:	Balkrishna, Sarojini, Bröer, Angelika, Welford, Scott M., Hatzoglou, Maria, Bröer, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis - genetics Acidosis - metabolism Amino acid transport Amino Acid Transport Systems, Neutral - biosynthesis Amino Acid Transport Systems, Neutral - genetics Animals Cells, Cultured Gene regulation HEK293 Cells HeLa Cells Hep G2 Cells Humans Hydrogen-Ion Concentration Mice Organ Specificity - genetics Original Paper Promoter methylation Promoter Regions, Genetic - genetics RNA, Messenger - genetics RNA, Messenger - metabolism SN1 Transcription, Genetic - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!