Production and Characterization of Monoclonal Antibodies Identifying Breast Tumor-Associated Antigens

We have generated a mouse monoclonal antibody (H23) against the retrovirus-like particles (human mammary tumor virus) released in vitro by the human breast adenocarcinoma cell line T47D. This antibody reacts specifically with a glycoprotein with an apparent molecular mass of 68 kDa (gp68) that is de...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1989-02, Vol.86 (4), p.1362-1366
Hauptverfasser:	Keydar, I., Chou, C. S., Hareuveni, M., Tsarfaty, I., Sahar, E., Selzer, G., Chaitchik, S., Hizi, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Animals Antibodies Antibodies, immunoglobulins Antibodies, Monoclonal Antigens Antigens, Surface - analysis Antigens, Viral, Tumor - analysis Biological and medical sciences Biomarkers, Tumor - analysis Breast cancer Breast ductal carcinoma Breast neoplasms Breast Neoplasms - analysis Breast Neoplasms - pathology Breasts Cell Line Enzyme-Linked Immunosorbent Assay Epitopes - analysis Female Flow Cytometry Fundamental and applied biological sciences. Psychology Fundamental immunology Glycoproteins Humans Immunoenzyme Techniques Mice Mice, Inbred BALB C Molecular immunology Molecular Weight Monoclonal antibodies Neoplasms - analysis Reference Values Retroviridae - isolation & purification Thyroid cancer Tumor cell line Tumors
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