Identification of a Region in the S1 Subunit of Pertussis Toxin that is Required for Enzymatic Activity and that Contributes to the Formation of a Neutralizing Antigenic Determinant

The S1 subunit of pertussis toxin possesses two regions (homology boxes), each spanning 8 residues, that are nearly identical in sequence to similarly located regions in the enzymatically active A fragments of two other ADP-ribosylating toxins: cholera toxin and Escherichia coli heatlabile toxin. Th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1988-07, Vol.85 (13), p.4667-4671
Hauptverfasser:	Cieplak, Witold, Burnette, W. Neal, Mar, Vernon L., Kaljot, Kaarel T., Morris, Charles F., Chen, Kenneth K., Sato, Hiroko, Keith, Jerry M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate Ribose - biosynthesis Amino Acid Sequence Amino acids Antibodies Bacteriology Biological and medical sciences Enzymes Epitopes Epitopes - immunology Fundamental and applied biological sciences. Psychology Microbiology Molecular Sequence Data Molecules Monoclonal antibodies Neutralization Tests Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Pertussis Toxin Plasmids Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - immunology Recombinant Fusion Proteins - metabolism Recombinant proteins Toxins Virulence Factors, Bordetella - genetics Virulence Factors, Bordetella - immunology Virulence Factors, Bordetella - metabolism Whooping cough
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!