The Apoptosis Repressor with a CARD Domain (ARC) Gene Is a Direct Hypoxia-Inducible Factor 1 Target Gene and Promotes Survival and Proliferation of VHL-Deficient Renal Cancer Cells
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Veröffentlicht in: | Molecular and Cellular Biology 2014-02, Vol.34 (4), p.739-751 |
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creator | Razorenova, Olga V. Castellini, Laura Colavitti, Renata Edgington, Laura E. Nicolau, Monica Huang, Xin Bedogni, Barbara Mills, Edward M. Bogyo, Matthew Giaccia, Amato J. |
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</description><identifier>ISSN: 0270-7306</identifier><identifier>ISSN: 1098-5549</identifier><identifier>EISSN: 1098-5549</identifier><identifier>DOI: 10.1128/MCB.00644-12</identifier><identifier>PMID: 24344197</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>AIDS-Related Complex - genetics ; Animals ; Apoptosis - genetics ; Apoptosis - physiology ; Carcinoma, Renal Cell - genetics ; Carcinoma, Renal Cell - metabolism ; Cell Hypoxia - genetics ; Cell Hypoxia - physiology ; Cell Proliferation ; Cell Survival ; Cells, Cultured ; Gene Expression Regulation, Neoplastic - genetics ; Gene Expression Regulation, Neoplastic - physiology ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit - genetics ; Hypoxia-Inducible Factor 1, alpha Subunit - metabolism ; Kidney Neoplasms - genetics ; Kidney Neoplasms - metabolism ; Kidney Neoplasms - pathology ; Mice ; Transcription Factors - genetics ; Transcription Factors - metabolism ; Tumor Suppressor Proteins - genetics ; Tumor Suppressor Proteins - metabolism ; Von Hippel-Lindau Tumor Suppressor Protein - genetics ; Von Hippel-Lindau Tumor Suppressor Protein - metabolism</subject><ispartof>Molecular and Cellular Biology, 2014-02, Vol.34 (4), p.739-751</ispartof><rights>Copyright © 2014, American Society for Microbiology 2014</rights><rights>Copyright © 2014, American Society for Microbiology. All Rights Reserved. 2014 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c490t-29a86c23ae91d7c853c92f84661d2738e2cb2b2dd9a75ad1a9931db246ee910f3</citedby><cites>FETCH-LOGICAL-c490t-29a86c23ae91d7c853c92f84661d2738e2cb2b2dd9a75ad1a9931db246ee910f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911479/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911479/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24344197$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Razorenova, Olga V.</creatorcontrib><creatorcontrib>Castellini, Laura</creatorcontrib><creatorcontrib>Colavitti, Renata</creatorcontrib><creatorcontrib>Edgington, Laura E.</creatorcontrib><creatorcontrib>Nicolau, Monica</creatorcontrib><creatorcontrib>Huang, Xin</creatorcontrib><creatorcontrib>Bedogni, Barbara</creatorcontrib><creatorcontrib>Mills, Edward M.</creatorcontrib><creatorcontrib>Bogyo, Matthew</creatorcontrib><creatorcontrib>Giaccia, Amato J.</creatorcontrib><title>The Apoptosis Repressor with a CARD Domain (ARC) Gene Is a Direct Hypoxia-Inducible Factor 1 Target Gene and Promotes Survival and Proliferation of VHL-Deficient Renal Cancer Cells</title><title>Molecular and Cellular Biology</title><addtitle>Mol Cell Biol</addtitle><description>Classifications
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</description><subject>AIDS-Related Complex - genetics</subject><subject>Animals</subject><subject>Apoptosis - genetics</subject><subject>Apoptosis - physiology</subject><subject>Carcinoma, Renal Cell - genetics</subject><subject>Carcinoma, Renal Cell - metabolism</subject><subject>Cell Hypoxia - genetics</subject><subject>Cell Hypoxia - physiology</subject><subject>Cell Proliferation</subject><subject>Cell Survival</subject><subject>Cells, Cultured</subject><subject>Gene Expression Regulation, Neoplastic - genetics</subject><subject>Gene Expression Regulation, Neoplastic - physiology</subject><subject>Humans</subject><subject>Hypoxia-Inducible Factor 1, alpha Subunit - genetics</subject><subject>Hypoxia-Inducible Factor 1, alpha Subunit - metabolism</subject><subject>Kidney Neoplasms - genetics</subject><subject>Kidney Neoplasms - metabolism</subject><subject>Kidney Neoplasms - pathology</subject><subject>Mice</subject><subject>Transcription Factors - genetics</subject><subject>Transcription Factors - metabolism</subject><subject>Tumor Suppressor Proteins - genetics</subject><subject>Tumor Suppressor Proteins - metabolism</subject><subject>Von Hippel-Lindau Tumor Suppressor Protein - genetics</subject><subject>Von Hippel-Lindau Tumor Suppressor Protein - metabolism</subject><issn>0270-7306</issn><issn>1098-5549</issn><issn>1098-5549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk9v0zAYhy0EYqVw44x8HBIZ_tckviCVdFsrFYFK4Wo5jtMaJXZmu-36vfiAeHSb4IA4WfL7vI_e1_4B8BqjC4xJ-f5T9fECoZyxDJMnYIQRL7PJhPGnYIRIgbKCovwMvAjhB0oYR_Q5OCOMMoZ5MQI_11sNp4MbogsmwJUevA7BeXgwcQslrKarGZy5XhoLz6er6i281lbDRUi1mfFaRTg_Du7WyGxhm50ydafhlVQxKTBcS7_R8dQibQO_eNe7qAP8uvN7s5fdw21nWu1lNM5C18Lv82U2061RRtuYZrIJrKRV2sNKd114CZ61sgv61f05Bt-uLtfVPFt-vl5U02WmGEcxI1yWuSJUao6bQpUTqjhpS5bnuCEFLTVRNalJ03BZTGSDJecUNzVhuU4dqKVj8OHkHXZ1rxuVpvGyE4M3vfRH4aQRf1es2YqN2wvKMWYFT4Lze4F3NzsdouhNUGkFabXbBYEnmFCSo_Qr_0UZJznHBN1Z351Q5V0IXrePE2Ek7jIhUibE70yI5B-DN39u8Qg_hCABxQkwtnW-lwfnu0ZEeeycb316dxME_Ycanjq3ZrM9pDgIGXrRq1pQJpgoKKe_AEYXz3Y</recordid><startdate>20140201</startdate><enddate>20140201</enddate><creator>Razorenova, Olga V.</creator><creator>Castellini, Laura</creator><creator>Colavitti, Renata</creator><creator>Edgington, Laura E.</creator><creator>Nicolau, Monica</creator><creator>Huang, Xin</creator><creator>Bedogni, Barbara</creator><creator>Mills, Edward M.</creator><creator>Bogyo, Matthew</creator><creator>Giaccia, Amato J.</creator><general>American Society for Microbiology</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>5PM</scope></search><sort><creationdate>20140201</creationdate><title>The Apoptosis Repressor with a CARD Domain (ARC) Gene Is a Direct Hypoxia-Inducible Factor 1 Target Gene and Promotes Survival and Proliferation of VHL-Deficient Renal Cancer Cells</title><author>Razorenova, Olga V. ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>24344197</pmid><doi>10.1128/MCB.00644-12</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
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subjects | AIDS-Related Complex - genetics Animals Apoptosis - genetics Apoptosis - physiology Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - metabolism Cell Hypoxia - genetics Cell Hypoxia - physiology Cell Proliferation Cell Survival Cells, Cultured Gene Expression Regulation, Neoplastic - genetics Gene Expression Regulation, Neoplastic - physiology Humans Hypoxia-Inducible Factor 1, alpha Subunit - genetics Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Kidney Neoplasms - genetics Kidney Neoplasms - metabolism Kidney Neoplasms - pathology Mice Transcription Factors - genetics Transcription Factors - metabolism Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism Von Hippel-Lindau Tumor Suppressor Protein - genetics Von Hippel-Lindau Tumor Suppressor Protein - metabolism |
title | The Apoptosis Repressor with a CARD Domain (ARC) Gene Is a Direct Hypoxia-Inducible Factor 1 Target Gene and Promotes Survival and Proliferation of VHL-Deficient Renal Cancer Cells |
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