Effects of a Hot-Water Extract of Porcini (Boletus aestivalis) Mushrooms on the Blood Pressure and Heart Rate of Spontaneously Hypertensive Rats

The repeated once-daily oral administration of a hot-water extract of porcini, Boletus aestivalis, mushrooms (WEP) to spontaneously hypertensive rats (SHR) for 18 weeks decreased the systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate. The WEP administration also decreased...

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Veröffentlicht in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2013, Vol.77 (8), p.1769-1772
Hauptverfasser: MIDOH, Naoki, MIYAZAWA, Noriko, EGUCHI, Fumio
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container_issue 8
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container_title Bioscience, biotechnology, and biochemistry
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creator MIDOH, Naoki
MIYAZAWA, Noriko
EGUCHI, Fumio
description The repeated once-daily oral administration of a hot-water extract of porcini, Boletus aestivalis, mushrooms (WEP) to spontaneously hypertensive rats (SHR) for 18 weeks decreased the systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate. The WEP administration also decreased blood urea nitrogen (BUN), creatinine (Cre), and triglyceride (TG), and increased high-density lipoprotein-cholesterol (HDL-C) in the blood, suggesting that WEP improved the status of hypertension, as well as the high heart rate and metabolic abnormalities involved in hypertension.
doi_str_mv 10.1271/bbb.130085
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source J-STAGE Free; Oxford University Press Journals All Titles (1996-Current); MEDLINE; Full-Text Journals in Chemistry (Open access); Freely Accessible Japanese Titles; EZB Electronic Journals Library
subjects Agaricales - chemistry
Animals
Antihypertensive Agents - administration & dosage
Antihypertensive Agents - chemistry
Basidiomycota - chemistry
blood pressure
Blood Pressure - drug effects
Boletus
heart rate
Heart Rate - drug effects
Humans
Hypertension - drug therapy
Hypertension - pathology
Plant Extracts - administration & dosage
Plant Extracts - chemistry
porcini mushroom
Rats
Water
title Effects of a Hot-Water Extract of Porcini (Boletus aestivalis) Mushrooms on the Blood Pressure and Heart Rate of Spontaneously Hypertensive Rats
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