Effects of a Hot-Water Extract of Porcini (Boletus aestivalis) Mushrooms on the Blood Pressure and Heart Rate of Spontaneously Hypertensive Rats
The repeated once-daily oral administration of a hot-water extract of porcini, Boletus aestivalis, mushrooms (WEP) to spontaneously hypertensive rats (SHR) for 18 weeks decreased the systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate. The WEP administration also decreased...
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Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2013, Vol.77 (8), p.1769-1772 |
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creator | MIDOH, Naoki MIYAZAWA, Noriko EGUCHI, Fumio |
description | The repeated once-daily oral administration of a hot-water extract of porcini, Boletus aestivalis, mushrooms (WEP) to spontaneously hypertensive rats (SHR) for 18 weeks decreased the systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate. The WEP administration also decreased blood urea nitrogen (BUN), creatinine (Cre), and triglyceride (TG), and increased high-density lipoprotein-cholesterol (HDL-C) in the blood, suggesting that WEP improved the status of hypertension, as well as the high heart rate and metabolic abnormalities involved in hypertension. |
doi_str_mv | 10.1271/bbb.130085 |
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source | J-STAGE Free; Oxford University Press Journals All Titles (1996-Current); MEDLINE; Full-Text Journals in Chemistry (Open access); Freely Accessible Japanese Titles; EZB Electronic Journals Library |
subjects | Agaricales - chemistry Animals Antihypertensive Agents - administration & dosage Antihypertensive Agents - chemistry Basidiomycota - chemistry blood pressure Blood Pressure - drug effects Boletus heart rate Heart Rate - drug effects Humans Hypertension - drug therapy Hypertension - pathology Plant Extracts - administration & dosage Plant Extracts - chemistry porcini mushroom Rats Water |
title | Effects of a Hot-Water Extract of Porcini (Boletus aestivalis) Mushrooms on the Blood Pressure and Heart Rate of Spontaneously Hypertensive Rats |
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