Mutational spectrum of N-hydroxy-N-acetyl-4-aminobiphenyl at exon 3 of the HPRT gene

4-Aminobiphenyl is a human bladder carcinogen present in many environmental sources, including cigarette smoke. It can be metabolized in two steps to the mutagen N-hydroxy-N-acetyl-4-aminobiphenyl (N-OH-AABP). In this study the mutational spectrum of N-OH-AABP-exposed human lymphoblastoid cells (TK6...

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Veröffentlicht in:	Biomarkers 2001, Vol.6 (4), p.262-273
Hauptverfasser:	ZAYAS-RIVERA, Beatriz, LIFANG ZHANG, GRANT, Stephen G, KEOHAVONG, Phouthone, DAY, Billy W
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chemical mutagenesis Hprt Aminobiphenyl Denaturant Gradient Gel Electrophoresis Mutational Spectrum Medical sciences Toxicology
Online-Zugang:	Volltext
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