Mutational spectrum of N-hydroxy-N-acetyl-4-aminobiphenyl at exon 3 of the HPRT gene
4-Aminobiphenyl is a human bladder carcinogen present in many environmental sources, including cigarette smoke. It can be metabolized in two steps to the mutagen N-hydroxy-N-acetyl-4-aminobiphenyl (N-OH-AABP). In this study the mutational spectrum of N-OH-AABP-exposed human lymphoblastoid cells (TK6...
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| Veröffentlicht in: | Biomarkers 2001, Vol.6 (4), p.262-273 |
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| container_end_page | 273 |
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| container_title | Biomarkers |
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| creator | ZAYAS-RIVERA, Beatriz LIFANG ZHANG GRANT, Stephen G KEOHAVONG, Phouthone DAY, Billy W |
| description | 4-Aminobiphenyl is a human bladder carcinogen present in many environmental sources, including cigarette smoke. It can be metabolized in two steps to the mutagen N-hydroxy-N-acetyl-4-aminobiphenyl (N-OH-AABP). In this study the mutational spectrum of N-OH-AABP-exposed human lymphoblastoid cells (TK6) was determined using HPRT |
| doi_str_mv | 10.1080/13547500010017367 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1354-750X |
| ispartof | Biomarkers, 2001, Vol.6 (4), p.262-273 |
| issn | 1354-750X 1366-5804 |
| language | eng |
| recordid | cdi_pubmed_primary_23889278 |
| source | Taylor & Francis; Taylor & Francis Medical Library - CRKN |
| subjects | Biological and medical sciences Chemical mutagenesis Hprt Aminobiphenyl Denaturant Gradient Gel Electrophoresis Mutational Spectrum Medical sciences Toxicology |
| title | Mutational spectrum of N-hydroxy-N-acetyl-4-aminobiphenyl at exon 3 of the HPRT gene |
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