Phosphatidylinositol 4-Kinase III Beta Is Essential for Replication of Human Rhinovirus and Its Inhibition Causes a Lethal Phenotype In Vivo
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2013-07, Vol.57 (7), p.3358-3368 |
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| creator | SPICKLER, Catherine LIPPENS, Julie VAILLANCOURT, Fréderic H DECOR, Anne O'MEARA, Jeff FRANTI, Michael GAUTHIER, Annick LABERGE, Marie-Kristine DESMEULES, Sophie BELLAVANCE, Edith GARNEAU, Michel GUO, Tim HUCKE, Oliver LEYSSEN, Pieter NEYTS, Johan |
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| doi_str_mv | 10.1128/AAC.00303-13 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.00303-13</identifier><identifier>PMID: 23650168</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>1-Phosphatidylinositol 4-Kinase ; 1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors ; 1-Phosphatidylinositol 4-Kinase - genetics ; 1-Phosphatidylinositol 4-Kinase - metabolism ; Animals ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Antiviral Agents - pharmacology ; Benzimidazoles - pharmacology ; Biological and medical sciences ; Cell Line, Tumor ; Cephalosporins ; Cephalosporins - pharmacology ; Common Cold - drug therapy ; Common Cold - virology ; Enterovirus ; Female ; HeLa Cells ; Human rhinovirus ; Humans ; Medical sciences ; Mice ; Pharmacology. Drug treatments ; Polymorphism, Single Nucleotide ; Rhinovirus ; Rhinovirus - drug effects ; Rhinovirus - enzymology ; Rhinovirus - growth & development ; RNA Interference ; RNA, Small Interfering ; Thiazoles ; Thiazoles - pharmacology ; Virus Replication - drug effects ; Virus Replication - genetics</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2013-07, Vol.57 (7), p.3358-3368</ispartof><rights>2014 INIST-CNRS</rights><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved.</rights><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved. 2013 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a550t-11a37c51b3bd79457b2612ae89c4180258e899ce4c43489aa5f09e79a49d4a563</citedby><cites>FETCH-LOGICAL-a550t-11a37c51b3bd79457b2612ae89c4180258e899ce4c43489aa5f09e79a49d4a563</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697394/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697394/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27480367$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23650168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SPICKLER, Catherine</creatorcontrib><creatorcontrib>LIPPENS, Julie</creatorcontrib><creatorcontrib>VAILLANCOURT, Fréderic H</creatorcontrib><creatorcontrib>DECOR, Anne</creatorcontrib><creatorcontrib>O'MEARA, Jeff</creatorcontrib><creatorcontrib>FRANTI, Michael</creatorcontrib><creatorcontrib>GAUTHIER, Annick</creatorcontrib><creatorcontrib>LABERGE, Marie-Kristine</creatorcontrib><creatorcontrib>DESMEULES, Sophie</creatorcontrib><creatorcontrib>BELLAVANCE, Edith</creatorcontrib><creatorcontrib>GARNEAU, Michel</creatorcontrib><creatorcontrib>GUO, Tim</creatorcontrib><creatorcontrib>HUCKE, Oliver</creatorcontrib><creatorcontrib>LEYSSEN, Pieter</creatorcontrib><creatorcontrib>NEYTS, Johan</creatorcontrib><title>Phosphatidylinositol 4-Kinase III Beta Is Essential for Replication of Human Rhinovirus and Its Inhibition Causes a Lethal Phenotype In Vivo</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>1-Phosphatidylinositol 4-Kinase</subject><subject>1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors</subject><subject>1-Phosphatidylinositol 4-Kinase - genetics</subject><subject>1-Phosphatidylinositol 4-Kinase - metabolism</subject><subject>Animals</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiviral Agents</subject><subject>Antiviral Agents - pharmacology</subject><subject>Benzimidazoles - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Cell Line, Tumor</subject><subject>Cephalosporins</subject><subject>Cephalosporins - pharmacology</subject><subject>Common Cold - drug therapy</subject><subject>Common Cold - virology</subject><subject>Enterovirus</subject><subject>Female</subject><subject>HeLa Cells</subject><subject>Human rhinovirus</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Pharmacology. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antiviral Agents</topic><topic>Antiviral Agents - pharmacology</topic><topic>Benzimidazoles - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Cell Line, Tumor</topic><topic>Cephalosporins</topic><topic>Cephalosporins - pharmacology</topic><topic>Common Cold - drug therapy</topic><topic>Common Cold - virology</topic><topic>Enterovirus</topic><topic>Female</topic><topic>HeLa Cells</topic><topic>Human rhinovirus</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>23650168</pmid><doi>10.1128/AAC.00303-13</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 2013-07, Vol.57 (7), p.3358-3368 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_pubmed_primary_23650168 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | 1-Phosphatidylinositol 4-Kinase 1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors 1-Phosphatidylinositol 4-Kinase - genetics 1-Phosphatidylinositol 4-Kinase - metabolism Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - pharmacology Benzimidazoles - pharmacology Biological and medical sciences Cell Line, Tumor Cephalosporins Cephalosporins - pharmacology Common Cold - drug therapy Common Cold - virology Enterovirus Female HeLa Cells Human rhinovirus Humans Medical sciences Mice Pharmacology. Drug treatments Polymorphism, Single Nucleotide Rhinovirus Rhinovirus - drug effects Rhinovirus - enzymology Rhinovirus - growth & development RNA Interference RNA, Small Interfering Thiazoles Thiazoles - pharmacology Virus Replication - drug effects Virus Replication - genetics |
| title | Phosphatidylinositol 4-Kinase III Beta Is Essential for Replication of Human Rhinovirus and Its Inhibition Causes a Lethal Phenotype In Vivo |
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