Gastric Acid Response to Antrum Distension in Man
Bergegårdh, S. & Olbe, L. Gastric acid response to antrum distension in man. Scand. J. Gastroent. 1975, 10, 171-176. Gastric acid secretion under basal conditions and in response to graded balloon distension (50 ml, 100 ml, 150 ml) of the antrum was determined in healthy subjects and in peptic u...
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| Veröffentlicht in: | Scandinavian journal of gastroenterology 1975-01, Vol.10 (2), p.171-176 |
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| container_title | Scandinavian journal of gastroenterology |
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| creator | Bergegårdh, S. Olbe, L. |
| description | Bergegårdh, S. & Olbe, L. Gastric acid response to antrum distension in man. Scand. J. Gastroent. 1975, 10, 171-176.
Gastric acid secretion under basal conditions and in response to graded balloon distension (50 ml, 100 ml, 150 ml) of the antrum was determined in healthy subjects and in peptic ulcer patients. In patients with a quiescent duodenal ulcer or a gastric ulcer antrum distension produced slight acid responses. The acid response to antrum distension was of quantitative importance only in patients with an active duodenal ulcer, amounting to 35% of the maximal acid response to pentagastrin. The healthy subjects did not respond with acid secretion to antrum distension. The pH of the gastric contents in the present series was 1.8-3.0, being lowest in patients with an active duodenal ulcer. Thus, the acid secretory effect of mechanical stimulation of the antrum seems qualitatively different in healthy subjects and ulcer patients, with a marked acid response in patients with an active duodenal ulcer. |
| doi_str_mv | 10.1080/00365521.1975.12096943 |
| format | Article |
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Gastric acid secretion under basal conditions and in response to graded balloon distension (50 ml, 100 ml, 150 ml) of the antrum was determined in healthy subjects and in peptic ulcer patients. In patients with a quiescent duodenal ulcer or a gastric ulcer antrum distension produced slight acid responses. The acid response to antrum distension was of quantitative importance only in patients with an active duodenal ulcer, amounting to 35% of the maximal acid response to pentagastrin. The healthy subjects did not respond with acid secretion to antrum distension. The pH of the gastric contents in the present series was 1.8-3.0, being lowest in patients with an active duodenal ulcer. Thus, the acid secretory effect of mechanical stimulation of the antrum seems qualitatively different in healthy subjects and ulcer patients, with a marked acid response in patients with an active duodenal ulcer.</description><identifier>ISSN: 0036-5521</identifier><identifier>EISSN: 1502-7708</identifier><identifier>DOI: 10.1080/00365521.1975.12096943</identifier><identifier>PMID: 235787</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Adult ; Aged ; Duodenal Ulcer - metabolism ; Female ; Gastric Acidity Determination ; Gastric Juice - secretion ; gastrin ; Humans ; Hydrogen-Ion Concentration ; Male ; Middle Aged ; Pentagastrin - pharmacology ; peptic ulcer ; pyloric antrum ; Pyloric Antrum - physiology ; Secretory Rate - drug effects ; Stimulation, Chemical ; stomach diseases ; Stomach Ulcer - metabolism</subject><ispartof>Scandinavian journal of gastroenterology, 1975-01, Vol.10 (2), p.171-176</ispartof><rights>1975 Informa UK Limited, trading as Taylor & Francis Group 1975</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c363t-bdbefc2adcb4f6d8b7c24c08d32e6aa300664d034f9fa5d7d1e29ac32c0339c63</citedby><cites>FETCH-LOGICAL-c363t-bdbefc2adcb4f6d8b7c24c08d32e6aa300664d034f9fa5d7d1e29ac32c0339c63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/00365521.1975.12096943$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/00365521.1975.12096943$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,59620,59726,60409,60515</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/235787$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bergegårdh, S.</creatorcontrib><creatorcontrib>Olbe, L.</creatorcontrib><title>Gastric Acid Response to Antrum Distension in Man</title><title>Scandinavian journal of gastroenterology</title><addtitle>Scand J Gastroenterol</addtitle><description>Bergegårdh, S. & Olbe, L. Gastric acid response to antrum distension in man. Scand. J. Gastroent. 1975, 10, 171-176.
Gastric acid secretion under basal conditions and in response to graded balloon distension (50 ml, 100 ml, 150 ml) of the antrum was determined in healthy subjects and in peptic ulcer patients. In patients with a quiescent duodenal ulcer or a gastric ulcer antrum distension produced slight acid responses. The acid response to antrum distension was of quantitative importance only in patients with an active duodenal ulcer, amounting to 35% of the maximal acid response to pentagastrin. The healthy subjects did not respond with acid secretion to antrum distension. The pH of the gastric contents in the present series was 1.8-3.0, being lowest in patients with an active duodenal ulcer. Thus, the acid secretory effect of mechanical stimulation of the antrum seems qualitatively different in healthy subjects and ulcer patients, with a marked acid response in patients with an active duodenal ulcer.</description><subject>Adult</subject><subject>Aged</subject><subject>Duodenal Ulcer - metabolism</subject><subject>Female</subject><subject>Gastric Acidity Determination</subject><subject>Gastric Juice - secretion</subject><subject>gastrin</subject><subject>Humans</subject><subject>Hydrogen-Ion Concentration</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pentagastrin - pharmacology</subject><subject>peptic ulcer</subject><subject>pyloric antrum</subject><subject>Pyloric Antrum - physiology</subject><subject>Secretory Rate - drug effects</subject><subject>Stimulation, Chemical</subject><subject>stomach diseases</subject><subject>Stomach Ulcer - metabolism</subject><issn>0036-5521</issn><issn>1502-7708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLxDAUhYP4Gkf_gUhX7jreJE3aLouPURgRRNchzQMibTImLTL_3ikz49bVXZzv3AMfQjcYFhgquAOgnDGCF7gu2QITqHld0CM0wwxIXpZQHaPZBOUTdY4uUvoCAFYW9Rk6JZSVVTlDeCnTEJ3KGuV09m7SOvhksiFkjR_i2GcPLg3GJxd85nz2Kv0lOrGyS-Zqf-fo8-nx4_45X70tX-6bVa4op0Pe6tZYRaRWbWG5rtpSkUJBpSkxXEoKwHmhgRa2tpLpUmNDaqkoUUBprTido9vd33UM36NJg-hdUqbrpDdhTKIiFTBCYQvyHahiSCkaK9bR9TJuBAYxqRIHVWJSJQ6qtsXr_cLY9kb_1XZutnGzi523IfbyJ8ROi0FuuhBtlF65JOg_E793OXeP</recordid><startdate>19750101</startdate><enddate>19750101</enddate><creator>Bergegårdh, S.</creator><creator>Olbe, L.</creator><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19750101</creationdate><title>Gastric Acid Response to Antrum Distension in Man</title><author>Bergegårdh, S. ; Olbe, L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c363t-bdbefc2adcb4f6d8b7c24c08d32e6aa300664d034f9fa5d7d1e29ac32c0339c63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Duodenal Ulcer - metabolism</topic><topic>Female</topic><topic>Gastric Acidity Determination</topic><topic>Gastric Juice - secretion</topic><topic>gastrin</topic><topic>Humans</topic><topic>Hydrogen-Ion Concentration</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pentagastrin - pharmacology</topic><topic>peptic ulcer</topic><topic>pyloric antrum</topic><topic>Pyloric Antrum - physiology</topic><topic>Secretory Rate - drug effects</topic><topic>Stimulation, Chemical</topic><topic>stomach diseases</topic><topic>Stomach Ulcer - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bergegårdh, S.</creatorcontrib><creatorcontrib>Olbe, L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bergegårdh, S.</au><au>Olbe, L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gastric Acid Response to Antrum Distension in Man</atitle><jtitle>Scandinavian journal of gastroenterology</jtitle><addtitle>Scand J Gastroenterol</addtitle><date>1975-01-01</date><risdate>1975</risdate><volume>10</volume><issue>2</issue><spage>171</spage><epage>176</epage><pages>171-176</pages><issn>0036-5521</issn><eissn>1502-7708</eissn><abstract>Bergegårdh, S. & Olbe, L. Gastric acid response to antrum distension in man. Scand. J. Gastroent. 1975, 10, 171-176.
Gastric acid secretion under basal conditions and in response to graded balloon distension (50 ml, 100 ml, 150 ml) of the antrum was determined in healthy subjects and in peptic ulcer patients. In patients with a quiescent duodenal ulcer or a gastric ulcer antrum distension produced slight acid responses. The acid response to antrum distension was of quantitative importance only in patients with an active duodenal ulcer, amounting to 35% of the maximal acid response to pentagastrin. The healthy subjects did not respond with acid secretion to antrum distension. The pH of the gastric contents in the present series was 1.8-3.0, being lowest in patients with an active duodenal ulcer. Thus, the acid secretory effect of mechanical stimulation of the antrum seems qualitatively different in healthy subjects and ulcer patients, with a marked acid response in patients with an active duodenal ulcer.</abstract><cop>England</cop><pub>Taylor & Francis</pub><pmid>235787</pmid><doi>10.1080/00365521.1975.12096943</doi><tpages>6</tpages></addata></record> |
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| ispartof | Scandinavian journal of gastroenterology, 1975-01, Vol.10 (2), p.171-176 |
| issn | 0036-5521 1502-7708 |
| language | eng |
| recordid | cdi_pubmed_primary_235787 |
| source | Taylor & Francis CRKN Medical; MEDLINE; Taylor & Francis Journals Complete |
| subjects | Adult Aged Duodenal Ulcer - metabolism Female Gastric Acidity Determination Gastric Juice - secretion gastrin Humans Hydrogen-Ion Concentration Male Middle Aged Pentagastrin - pharmacology peptic ulcer pyloric antrum Pyloric Antrum - physiology Secretory Rate - drug effects Stimulation, Chemical stomach diseases Stomach Ulcer - metabolism |
| title | Gastric Acid Response to Antrum Distension in Man |
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