Effects of Mobilization Regimens in Donors on Outcomes of Hematopoietic Cell Transplantation in Miniature Swine

Toxicities and complications associated with hematopoietic cell transplantation currently limit this potentially curative therapy for malignant and nonmalignant blood disorders. Miniature swine provide a clinically relevant model for studies to improve posttransplantation outcomes. Miniature swine r...

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Veröffentlicht in:	Comparative medicine 2012-12, Vol.62 (6), p.487-494
Hauptverfasser:	Matar, Abraham J, Crepeau, Rebecca L, Pathiraja, Vimukthi, Robson, Simon, Fishman, Jay A, Spitzer, Thomas R, Sachs, David H, Huang, Christene A, Duran-Struuck, Raimon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cyclosporine - therapeutic use Cytokines - pharmacology DNA Primers - genetics Graft Survival - physiology Hematologic Diseases - therapy Hematopoietic Stem Cell Mobilization - methods Hematopoietic Stem Cell Transplantation - adverse effects Immunotoxins - therapeutic use Leukapheresis - methods Polymerase Chain Reaction Swine Swine Models Swine, Miniature Transplantation Conditioning - methods Treatment Outcome Whole-Body Irradiation
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