31P NMR studies of ATP concentrations and Pi-ATP exchange in the rat kidney in Vivo: Effects of inhibiting and stimulating renal metabolism

Previous investigators found that cyanide (CN−) is a potent inhibitor of renal Na+ transport, while the uncoupling agent 2,4‐dinitrophenol (DNP) and fructose (both which lower ATP levels) are weak transport inhibitors. To examine the disparate effects of these substances measurements of ATP were per...

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Veröffentlicht in:	Magnetic resonance in medicine 1990-06, Vol.14 (3), p.445-460
Hauptverfasser:	Shine, Nancy, Xuan, Ai, Weiner, Michael W.
Format:	Artikel
Sprache:	eng
Schlagworte:	2,4-Dinitrophenol Adenosine Triphosphate - metabolism Animals Biological and medical sciences Dinitrophenols - pharmacology Fructose - pharmacology Fundamental and applied biological sciences. Psychology Kidney - drug effects Kidney - metabolism Magnetic Resonance Spectroscopy Oxygen Consumption Phosphates - metabolism Rats Rats, Inbred Strains Sodium - metabolism Sodium Cyanide - pharmacology Vertebrates: urinary system
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