Turning a Spermatogenic Wave into a Tsunami: Synchronizing Murine Spermatogenesis Using WIN 18,446

The BDADs (bis-[dichloroacetyl]-diamines) are compounds that can inhibit spermatogenesis via blocking the metabolism of vitamin A. We utilized one specific BDAD, WIN 18,446, to manipulate the endogenous production of retinoic acid (RA) in the testis to further investigate the action of this compound...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biology of reproduction 2013-02, Vol.88 (2), p.40
Hauptverfasser:	HOGARTH, Cathryn A, EVANOFF, Ryan, MITCHELL, Debra, KENT, Travis, SMALL, Christopher, AMORY, John K, GRISWOLD, Michael D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Differentiation - drug effects Cell Differentiation - physiology Diamines - pharmacology Fundamental and applied biological sciences. Psychology Male Mice Models, Animal Spermatogenesis - drug effects Spermatogenesis - physiology Testis - cytology Testis - embryology Testis - metabolism Tretinoin - metabolism Vertebrates: reproduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!