Pharmacokinetics and Biodistribution Study of 7A7 Anti-Mouse Epidermal Growth Factor Receptor Monoclonal Antibody and Its F(ab')(2) Fragment in an Immunocompetent Mouse Model

Immunocompetent mice, Fc receptor γ-chain deficient mice (Fcer1g(-/-)), and molecular tools as F(ab')(2) bivalent fragments appear as the most suitable biological models to study the mechanisms of the action of anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (mAbs). In vivo e...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ISRN pharmacology 2012, Vol.2012, p.417515
Hauptverfasser:	Rabasa Capote, Ailem, González, Jorge Ernesto, Rodríguez-Vera, Leyanis, López, Armando, Sánchez Ramírez, Belinda, Garrido Hidalgo, Greta
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!