Promoter and histone methylation and p16(INK4A) gene expression in colon cancer

The inactivation of the cyclin-dependent kinase inhibitor p16(INK4A) gene by hypermethylation is observed in numerous types of cancer. New findings indicate that DNA and histone methylation act in concert in gene silencing. In this study, we investigated the methylation status of the p16(INK4A) gene...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Experimental and therapeutic medicine 2012-11, Vol.4 (5), p.865
Hauptverfasser:	Yoruker, Ebru Esin, Mert, Ufuk, Bugra, Dursun, Yamaner, Sumer, Dalay, Nejat
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!