Aquaporin-2 Levels in vitro and in vivo are Regulated by VACM-1, a Cul 5 Gene

Background: In the renal collecting duct, vasopressin regulates water permeability by a process that involves stimulation of adenylyl cyclase activity, cAMP production and subsequent translocation of water channel aquaporin-2 (AQP2) into the apical plasma membrane. We have previously shown that in c...

Ausführliche Beschreibung