Palette of fluorinated voltage-sensitive hemicyanine dyes

Optical recording of membrane potential permits spatially resolved measurement of electrical activity in subcellular regions of single cells, which would be inaccessible to electrodes, and imaging of spatiotemporal patterns of action potential propagation in excitable tissues, such as the brain or h...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2012-12, Vol.109 (50), p.20443-20448
Hauptverfasser:	Yan, Ping, Acker, Corey D, Zhou, Wen-Liang, Lee, Peter, Bollensdorff, Christian, Negrean, Adrian, Lotti, Jacopo, Sacconi, Leonardo, Antic, Srdjan D, Kohl, Peter, Mansvelder, Huibert D, Pavone, Francesco S, Loew, Leslie M
Format:	Artikel
Sprache:	eng
Schlagworte:	absorbance Action Potentials Animals Atoms & subatomic particles Biological Sciences Biophysical Phenomena brain Brain - physiology Calcium Calcium Signaling Carbocyanines - chemistry Cell membranes Cells Chromophores Coloring Agents - chemistry Dendritic spines Dendritic Spines - physiology Dyes Electric potential Electrodes Female Fluorescence Fluorescent Dyes - chemistry fluorine Fluorine - chemistry Guinea Pigs heart Heart - physiology image analysis Imaging In Vitro Techniques Membranes Mice Microscopy, Fluorescence, Multiphoton - instrumentation Molecular Structure Neurons Optical Phenomena photostability physiological state Purkinje Cells - physiology Rats Rats, Wistar Spectrophotometry Tissues Wave excitation Wavelengths
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