Role of inositol 1,4,5-trisphosphate in the regulation of ventricular Ca(2+) signaling in intact mouse heart

Inositol 1,4,5-trisphosphate (InsP(3)R)-mediated Ca(2+) signaling is a major pathway regulating multiple cellular functions in excitable and non-excitable cells. Although InsP(3)-mediated Ca(2+) signaling has been extensively described, its influence on ventricular myocardium activity has not been a...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2012-12, Vol.53 (6), p.768
Hauptverfasser:	Escobar, Ariel L, Perez, Claudia G, Reyes, Mariano E, Lucero, Sarah G, Kornyeyev, Dmytro, Mejía-Alvarez, Rafael, Ramos-Franco, Josefina
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Animals Calcium - metabolism Calcium Signaling - drug effects Dose-Response Relationship, Drug Heart - drug effects Heart - physiology Heart Ventricles - drug effects Heart Ventricles - metabolism In Vitro Techniques Inositol 1,4,5-Trisphosphate - metabolism Inositol 1,4,5-Trisphosphate - pharmacology Inositol 1,4,5-Trisphosphate Receptors - metabolism Kinetics Mice Myocytes, Cardiac - metabolism Protein Binding Ryanodine Receptor Calcium Release Channel - metabolism
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