An automated two-phase system for hydrogel microbead production

Polymeric beads have been used for protection and delivery of bioactive materials, such as drugs and cells, for different biomedical applications. Here, we present a generic two-phase system for the production of polymeric microbeads of gellan gum or alginate, based on a combination of in situ polym...

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Veröffentlicht in:	Biofabrication 2012-09, Vol.4 (3), p.035003-1-10
Hauptverfasser:	Coutinho, Daniela F, Ahari, Amir F, Kachouie, Nezamoddin N, Gomes, Manuela E, Neves, Nuno M, Reis, Rui L, Khademhosseini, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Alginates - chemistry Animals automated system Automation bead formation Beads Cell Line, Tumor Cell- and Tissue-Based Therapy Crosslinking Droplets Drug Carriers - chemistry Drug delivery systems encapsulation Fluorescent Dyes - chemistry gellan gum Glucuronic Acid - chemistry Hexuronic Acids - chemistry Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry Hydrophobic and Hydrophilic Interactions ionic polymers Mice Microorganisms Microspheres Needles NIH 3T3 Cells Phase separation Polymerization Polymers - chemistry Polysaccharides, Bacterial - chemistry
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