Potential applications of bacteriorhodopsin mutants
Bacteriorhodopsin (BR), a model system in biotechnology, is a G-protein dependent trans membrane protein which serves as a light driven proton pump in the cell membrane of Halobacterium salinarum. Due to the linkage of retinal to the protein, it seems colored and has numbers of versatile properties....
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| Veröffentlicht in: | Bioengineered 2012-11, Vol.3 (6), p.326-328 |
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| creator | Saeedi, P. Moosaabadi, J. Mohammadian Sebtahmadi, S. Sina Mehrabadi, J. Fallah Behmanesh, M. Mekhilef, S. |
| description | Bacteriorhodopsin (BR), a model system in biotechnology, is a G-protein dependent trans membrane protein which serves as a light driven proton pump in the cell membrane of Halobacterium salinarum. Due to the linkage of retinal to the protein, it seems colored and has numbers of versatile properties. As in vitro culture of the Halobacteria is very difficult, and isolation is time consuming and usually inefficient, production of genetically modified constructs of the protein is essential. There are three important characteristics based on protein catalytic cycle and molecular functions of photo-electric, photochromic and proton transporting, which makes this protein as a strategic molecule with potential applications in biotechnology. Such applications include protein films, used in artificial retinal implants, light modulators, three-dimensional optical memories, color photochromic sensors, photochromic and electrochromic papers and ink, biological camouflage and photo detectors for biodefense and non-defense purposes. |
| doi_str_mv | 10.4161/bioe.21445 |
| format | Article |
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Mohammadian ; Sebtahmadi, S. Sina ; Mehrabadi, J. Fallah ; Behmanesh, M. ; Mekhilef, S.</creator><creatorcontrib>Saeedi, P. ; Moosaabadi, J. Mohammadian ; Sebtahmadi, S. Sina ; Mehrabadi, J. Fallah ; Behmanesh, M. ; Mekhilef, S.</creatorcontrib><description>Bacteriorhodopsin (BR), a model system in biotechnology, is a G-protein dependent trans membrane protein which serves as a light driven proton pump in the cell membrane of Halobacterium salinarum. Due to the linkage of retinal to the protein, it seems colored and has numbers of versatile properties. As in vitro culture of the Halobacteria is very difficult, and isolation is time consuming and usually inefficient, production of genetically modified constructs of the protein is essential. There are three important characteristics based on protein catalytic cycle and molecular functions of photo-electric, photochromic and proton transporting, which makes this protein as a strategic molecule with potential applications in biotechnology. Such applications include protein films, used in artificial retinal implants, light modulators, three-dimensional optical memories, color photochromic sensors, photochromic and electrochromic papers and ink, biological camouflage and photo detectors for biodefense and non-defense purposes.</description><identifier>ISSN: 2165-5979</identifier><identifier>EISSN: 2165-5987</identifier><identifier>DOI: 10.4161/bioe.21445</identifier><identifier>PMID: 22895057</identifier><language>eng</language><publisher>United States: Taylor & Francis</publisher><subject>artificial retina ; bacteriorhodopsin ; Bacteriorhodopsins - chemistry ; Bacteriorhodopsins - genetics ; Binding ; bio-defense ; bioelectronics ; Biology ; Bioscience ; Biosensing Techniques - instrumentation ; Biosensing Techniques - methods ; Calcium ; Cancer ; Cell ; Cycle ; electro-chromic ; Halobacterium salinarum - chemistry ; Halobacterium salinarum - metabolism ; Halobacterium salinarum - radiation effects ; Ion Transport ; Landes ; Light ; light memory ; Mini Review ; Models, Biological ; mutants ; Mutation ; nano structure ; Nanostructures - chemistry ; Organogenesis ; photo activation ; photo-chromic ; Photochemical Processes ; Protein Engineering ; Proteins ; Purple Membrane - chemistry ; Purple Membrane - metabolism ; Purple Membrane - radiation effects ; Retinal Pigments - biosynthesis ; Retinal Pigments - chemistry ; Retinal Pigments - therapeutic use ; Transplants</subject><ispartof>Bioengineered, 2012-11, Vol.3 (6), p.326-328</ispartof><rights>Copyright © 2012 Landes Bioscience 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c512t-b989038b350e6acaa3787f3d757d9751d7ebb2316bff0e71473550df8877898b3</citedby><cites>FETCH-LOGICAL-c512t-b989038b350e6acaa3787f3d757d9751d7ebb2316bff0e71473550df8877898b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489707/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489707/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22895057$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saeedi, P.</creatorcontrib><creatorcontrib>Moosaabadi, J. Mohammadian</creatorcontrib><creatorcontrib>Sebtahmadi, S. Sina</creatorcontrib><creatorcontrib>Mehrabadi, J. Fallah</creatorcontrib><creatorcontrib>Behmanesh, M.</creatorcontrib><creatorcontrib>Mekhilef, S.</creatorcontrib><title>Potential applications of bacteriorhodopsin mutants</title><title>Bioengineered</title><addtitle>Bioengineered</addtitle><description>Bacteriorhodopsin (BR), a model system in biotechnology, is a G-protein dependent trans membrane protein which serves as a light driven proton pump in the cell membrane of Halobacterium salinarum. Due to the linkage of retinal to the protein, it seems colored and has numbers of versatile properties. As in vitro culture of the Halobacteria is very difficult, and isolation is time consuming and usually inefficient, production of genetically modified constructs of the protein is essential. There are three important characteristics based on protein catalytic cycle and molecular functions of photo-electric, photochromic and proton transporting, which makes this protein as a strategic molecule with potential applications in biotechnology. Such applications include protein films, used in artificial retinal implants, light modulators, three-dimensional optical memories, color photochromic sensors, photochromic and electrochromic papers and ink, biological camouflage and photo detectors for biodefense and non-defense purposes.</description><subject>artificial retina</subject><subject>bacteriorhodopsin</subject><subject>Bacteriorhodopsins - chemistry</subject><subject>Bacteriorhodopsins - genetics</subject><subject>Binding</subject><subject>bio-defense</subject><subject>bioelectronics</subject><subject>Biology</subject><subject>Bioscience</subject><subject>Biosensing Techniques - instrumentation</subject><subject>Biosensing Techniques - methods</subject><subject>Calcium</subject><subject>Cancer</subject><subject>Cell</subject><subject>Cycle</subject><subject>electro-chromic</subject><subject>Halobacterium salinarum - chemistry</subject><subject>Halobacterium salinarum - metabolism</subject><subject>Halobacterium salinarum - radiation effects</subject><subject>Ion Transport</subject><subject>Landes</subject><subject>Light</subject><subject>light memory</subject><subject>Mini Review</subject><subject>Models, Biological</subject><subject>mutants</subject><subject>Mutation</subject><subject>nano structure</subject><subject>Nanostructures - chemistry</subject><subject>Organogenesis</subject><subject>photo activation</subject><subject>photo-chromic</subject><subject>Photochemical Processes</subject><subject>Protein Engineering</subject><subject>Proteins</subject><subject>Purple Membrane - chemistry</subject><subject>Purple Membrane - metabolism</subject><subject>Purple Membrane - radiation effects</subject><subject>Retinal Pigments - biosynthesis</subject><subject>Retinal Pigments - chemistry</subject><subject>Retinal Pigments - therapeutic use</subject><subject>Transplants</subject><issn>2165-5979</issn><issn>2165-5987</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMoKurGHyBdC9U8Jk1mI6j4KAgVH-twJw8bmSZDEhX_vVOrrYLgKhdyvnPPPQjtE3xUkRE5bny0R5RUFV9D25SM-JDXUqwvZ1Fvob2cnzHGBLOKC7mJtiiVNcdcbCN2G4sNxUM7gK5rvYbiY8iD6AYN6GKTj2kaTeyyD4PZS4FQ8i7acNBmu_f17qDHy4uH8-vhzeRqfH56M9Sc0DJsalljJhvGsR2BBmBCCseM4MLUghMjbNNQRkaNc9gKUgnGOTZOSiFk3XM76GTh2700M2t0nzNBq7rkZ5DeVQSvfv8EP1VP8VWxStYCi97gcGGgU8w5WbdkCVbz9tS8PfXZXi8--LltKf3uqhdUC0ELwdjco1l7G7RdSTGhZ-PJ2ePVPaayulOdcT1G_8E-Q0AqXrerMHwB-eBimsFbTK1RBd7bmFyCoH1W7I8jPgDpcaMr</recordid><startdate>20121101</startdate><enddate>20121101</enddate><creator>Saeedi, P.</creator><creator>Moosaabadi, J. Mohammadian</creator><creator>Sebtahmadi, S. Sina</creator><creator>Mehrabadi, J. Fallah</creator><creator>Behmanesh, M.</creator><creator>Mekhilef, S.</creator><general>Taylor & Francis</general><general>Landes Bioscience</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20121101</creationdate><title>Potential applications of bacteriorhodopsin mutants</title><author>Saeedi, P. ; Moosaabadi, J. Mohammadian ; Sebtahmadi, S. Sina ; Mehrabadi, J. Fallah ; Behmanesh, M. ; Mekhilef, S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c512t-b989038b350e6acaa3787f3d757d9751d7ebb2316bff0e71473550df8877898b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>artificial retina</topic><topic>bacteriorhodopsin</topic><topic>Bacteriorhodopsins - chemistry</topic><topic>Bacteriorhodopsins - genetics</topic><topic>Binding</topic><topic>bio-defense</topic><topic>bioelectronics</topic><topic>Biology</topic><topic>Bioscience</topic><topic>Biosensing Techniques - instrumentation</topic><topic>Biosensing Techniques - methods</topic><topic>Calcium</topic><topic>Cancer</topic><topic>Cell</topic><topic>Cycle</topic><topic>electro-chromic</topic><topic>Halobacterium salinarum - chemistry</topic><topic>Halobacterium salinarum - metabolism</topic><topic>Halobacterium salinarum - radiation effects</topic><topic>Ion Transport</topic><topic>Landes</topic><topic>Light</topic><topic>light memory</topic><topic>Mini Review</topic><topic>Models, Biological</topic><topic>mutants</topic><topic>Mutation</topic><topic>nano structure</topic><topic>Nanostructures - chemistry</topic><topic>Organogenesis</topic><topic>photo activation</topic><topic>photo-chromic</topic><topic>Photochemical Processes</topic><topic>Protein Engineering</topic><topic>Proteins</topic><topic>Purple Membrane - chemistry</topic><topic>Purple Membrane - metabolism</topic><topic>Purple Membrane - radiation effects</topic><topic>Retinal Pigments - biosynthesis</topic><topic>Retinal Pigments - chemistry</topic><topic>Retinal Pigments - therapeutic use</topic><topic>Transplants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saeedi, P.</creatorcontrib><creatorcontrib>Moosaabadi, J. 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There are three important characteristics based on protein catalytic cycle and molecular functions of photo-electric, photochromic and proton transporting, which makes this protein as a strategic molecule with potential applications in biotechnology. Such applications include protein films, used in artificial retinal implants, light modulators, three-dimensional optical memories, color photochromic sensors, photochromic and electrochromic papers and ink, biological camouflage and photo detectors for biodefense and non-defense purposes.</abstract><cop>United States</cop><pub>Taylor & Francis</pub><pmid>22895057</pmid><doi>10.4161/bioe.21445</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | artificial retina bacteriorhodopsin Bacteriorhodopsins - chemistry Bacteriorhodopsins - genetics Binding bio-defense bioelectronics Biology Bioscience Biosensing Techniques - instrumentation Biosensing Techniques - methods Calcium Cancer Cell Cycle electro-chromic Halobacterium salinarum - chemistry Halobacterium salinarum - metabolism Halobacterium salinarum - radiation effects Ion Transport Landes Light light memory Mini Review Models, Biological mutants Mutation nano structure Nanostructures - chemistry Organogenesis photo activation photo-chromic Photochemical Processes Protein Engineering Proteins Purple Membrane - chemistry Purple Membrane - metabolism Purple Membrane - radiation effects Retinal Pigments - biosynthesis Retinal Pigments - chemistry Retinal Pigments - therapeutic use Transplants |
| title | Potential applications of bacteriorhodopsin mutants |
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