Draft Genome of Streptomyces tsukubaensis NRRL 18488, the Producer of the Clinically Important Immunosuppressant Tacrolimus (FK506)

The macrocyclic polyketide tacrolimus (FK506) is a potent immunosuppressant that prevents T-cell proliferation produced solely by Streptomyces species. We report here the first draft genome sequence of a true FK506 producer, Streptomyces tsukubaensis NRRL 18488, the first tacrolimus-producing strain...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Bacteriology 2012-07, Vol.194 (14), p.3756-3757
Hauptverfasser:	Barreiro, Carlos, Prieto, Carlos, Sola-Landa, Alberto, Solera, Elena, Martínez-Castro, Miriam, Pérez-Redondo, Rosario, García-Estrada, Carlos, Aparicio, Jesús F, Fernández-Martínez, Lorena T, Santos-Aberturas, Javier, Salehi-Najafabadi, Zahra, Rodríguez-García, Antonio, Tauch, Andreas, Martín, Juan F
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bacteriology biosynthesis Gene Expression Regulation, Bacterial - physiology genes Genome Announcements Genome, Bacterial Genomes Immunosuppressive Agents - metabolism Molecular Sequence Data nucleotide sequences Streptomyces Streptomyces - classification Streptomyces - genetics Streptomyces - metabolism T cell receptors T-lymphocytes tacrolimus Tacrolimus - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!