Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy

We describe voltage-switching mode scanning electrochemical microscopy (VSM-SECM), in which a single SECM tip electrode was used to acquire high-quality topographical and electrochemical images of living cells simultaneously. This was achieved by switching the applied voltage so as to change the far...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2012-07, Vol.109 (29), p.11540-11545
Hauptverfasser:	Takahashi, Yasufumi, Shevchuk, Andrew I., Novak, Pavel, Babakinejad, Babak, Macpherson, Julie, Unwin, Patrick R., Shiku, Hitoshi, Gorelik, Julia, Klenerman, David, Korchev, Yuri E., Matsue, Tomokazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbon Cell Line, Tumor Cells confocal microscopy Diagnostic Imaging - methods Electric current Electrochemical cells Electrochemical Techniques - methods electrochemistry ELECTROCHEMISTRY: SPECIAL FEATURE Electrodes Fluorescence Humans image analysis Imaging membrane proteins Microscopy Microscopy, Scanning Probe - methods Nanomaterials Nanostructures - chemistry Neurons Neurotransmitters PC12 Cells Physical Sciences Rats Scientific imaging Steady state current Time Factors Topography
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