Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2012-07, Vol.56 (7), p.3928-3935 |
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| creator | VANICHTANANKUL, Jarunee TAWEECHAI, Supannee UTTAMAPINANT, Chayasith CHITNUMSUB, Penchit VILAIVAN, Tirayut YUTHAVONG, Yongyuth KAMCHONWONGPAISAN, Sumalee |
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| doi_str_mv | 10.1128/AAC.00301-12 |
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1752 N Street N.W. • Washington DC 20036
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| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3928-3935 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_pubmed_primary_22526319 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials Antimalarials - pharmacology Biological and medical sciences Drug Resistance - genetics Folic Acid Antagonists Folic Acid Antagonists - pharmacology Mechanisms of Resistance Medical sciences Mutation Pharmacology. Drug treatments Plasmodium falciparum Plasmodium falciparum - drug effects Plasmodium falciparum - enzymology Plasmodium falciparum - genetics Proguanil Proguanil - pharmacology Tetrahydrofolate Dehydrogenase Tetrahydrofolate Dehydrogenase - chemistry Tetrahydrofolate Dehydrogenase - genetics Tetrahydrofolate Dehydrogenase - metabolism Triazines Triazines - pharmacology |
| title | Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil |
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