Improvement of spread-out Bragg peak flatness for a carbon-ion beam by the use of a ridge filter with a ripple filter

We have developed a novel design method of ridge filters for carbon-ion therapy using a broad-beam delivery system to improve the flatness of a biologically effective dose in the spread-out Bragg peak (SOBP). So far, the flatness of the SOBP is limited to about ±5% for carbon beams since the weight...

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Veröffentlicht in:	Physics in medicine & biology 2012-03, Vol.57 (6), p.1717-1731
Hauptverfasser:	Hara, Yousuke, Takada, Yoshihisa, Hotta, Kenji, Tansho, Ryohei, Nihei, Tetsuya, Suzuki, Yojiro, Nagafuchi, Kosuke, Kawai, Ryuichi, Tanabe, Masaki, Mizutani, Shohei, Himukai, Takeshi, Matsufuji, Naruhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysical Phenomena broad-beam delivery method Carbon - therapeutic use carbon therapy Equipment Design Filtration - instrumentation Heavy Ions - therapeutic use Humans Radiotherapy, High-Energy - instrumentation Radiotherapy, High-Energy - statistics & numerical data Relative Biological Effectiveness ridge filter ripple filter SOBP
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