Hypoxic-ischemic damage and the neuroprotective effects of GM1 ganglioside

In vitro studies have shown that monosialoganglioside GM1 reduces excitatory amino acid-related neurotoxicity by limiting the downstream consequences of abusive excitatory amino acid receptor stimulation. Systemic administration of GM1 appears to be efficacious in reducing acute neuronal damage and...

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Veröffentlicht in:	Stroke (1970) 1990-11, Vol.21 (11 Suppl), p.III95
Hauptverfasser:	Leon, A, Lipartiti, M, Seren, M S, Lazzaro, A, Mazzari, S, Koga, T, Toffano, G, Skaper, S D
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - toxicity Animals Brain - drug effects Brain Ischemia - metabolism Central Nervous System - physiopathology G(M1) Ganglioside - pharmacology Hypoxia, Brain - metabolism Neurons - drug effects Neurons - metabolism
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