A Portable Continuous Blood Purification Machine for Emergency Rescue in Disasters
Background: Continuous renal replacement therapy plays an important role in emergency rescue. Currently, no continuous renal replacement therapy machine can be used under unstable conditions as the fluid flow of these machines is controlled electronically. A novel machine that can provide emergency...
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| Veröffentlicht in: | Blood purification 2012-01, Vol.33 (4), p.227-237 |
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| container_title | Blood purification |
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| creator | He, Ping Zhou, Chunhua Li, Hongyan Yu, Yongwu Dong, Zhen Wen, Yuanyuan Li, Ping Tang, Wenhong Wang, Xue |
| description | Background: Continuous renal replacement therapy plays an important role in emergency rescue. Currently, no continuous renal replacement therapy machine can be used under unstable conditions as the fluid flow of these machines is controlled electronically. A novel machine that can provide emergency continuous renal replacement therapy in disaster rescue is therefore needed. Methods: Based on a volumetric metering method, a prototype portable continuous blood purifier based on a volumetric metering method was developed. Basic performance tests, special environmental tests, animal experiments and clinical use of the novel machine were completed to test and verify its performance under unstable conditions. Results: All tests completed showed that the machine met the requirements of the national industry standards with a size reduced to approximately one half of the Baxter Aquarius machine. The clearance of harmful substances by the machine described here was equal to that of the Baxter Aquarius machine and was adequate for clinical purposes. Conclusions: The novel prototype performed well in all situations tested and can aid rescue work on disaster sites. |
| doi_str_mv | 10.1159/000336092 |
| format | Article |
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Currently, no continuous renal replacement therapy machine can be used under unstable conditions as the fluid flow of these machines is controlled electronically. A novel machine that can provide emergency continuous renal replacement therapy in disaster rescue is therefore needed. Methods: Based on a volumetric metering method, a prototype portable continuous blood purifier based on a volumetric metering method was developed. Basic performance tests, special environmental tests, animal experiments and clinical use of the novel machine were completed to test and verify its performance under unstable conditions. Results: All tests completed showed that the machine met the requirements of the national industry standards with a size reduced to approximately one half of the Baxter Aquarius machine. The clearance of harmful substances by the machine described here was equal to that of the Baxter Aquarius machine and was adequate for clinical purposes. Conclusions: The novel prototype performed well in all situations tested and can aid rescue work on disaster sites.</description><identifier>ISSN: 0253-5068</identifier><identifier>EISSN: 1421-9735</identifier><identifier>DOI: 10.1159/000336092</identifier><identifier>PMID: 22343795</identifier><identifier>CODEN: BLPUDO</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject>Acute Kidney Injury - blood ; Acute Kidney Injury - physiopathology ; Acute Kidney Injury - therapy ; Adult ; Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Animals ; Biological and medical sciences ; Dogs ; Emergency and intensive care: renal failure. Dialysis management ; Emergency Medical Services ; Equipment Design ; Female ; Hemofiltration - instrumentation ; Humans ; Intensive care medicine ; Kidney - physiopathology ; Male ; Medical sciences ; Middle Aged ; Original Paper ; Renal Replacement Therapy - instrumentation</subject><ispartof>Blood purification, 2012-01, Vol.33 (4), p.227-237</ispartof><rights>2012 S. Karger AG, Basel</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012 S. Karger AG, Basel.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c336t-87a52562f0493d2c227520324fc97c5ce38950ca4829b46034cc594f334d82a3</citedby><cites>FETCH-LOGICAL-c336t-87a52562f0493d2c227520324fc97c5ce38950ca4829b46034cc594f334d82a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2423,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26098487$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22343795$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>He, Ping</creatorcontrib><creatorcontrib>Zhou, Chunhua</creatorcontrib><creatorcontrib>Li, Hongyan</creatorcontrib><creatorcontrib>Yu, Yongwu</creatorcontrib><creatorcontrib>Dong, Zhen</creatorcontrib><creatorcontrib>Wen, Yuanyuan</creatorcontrib><creatorcontrib>Li, Ping</creatorcontrib><creatorcontrib>Tang, Wenhong</creatorcontrib><creatorcontrib>Wang, Xue</creatorcontrib><title>A Portable Continuous Blood Purification Machine for Emergency Rescue in Disasters</title><title>Blood purification</title><addtitle>Blood Purif</addtitle><description>Background: Continuous renal replacement therapy plays an important role in emergency rescue. Currently, no continuous renal replacement therapy machine can be used under unstable conditions as the fluid flow of these machines is controlled electronically. A novel machine that can provide emergency continuous renal replacement therapy in disaster rescue is therefore needed. Methods: Based on a volumetric metering method, a prototype portable continuous blood purifier based on a volumetric metering method was developed. Basic performance tests, special environmental tests, animal experiments and clinical use of the novel machine were completed to test and verify its performance under unstable conditions. Results: All tests completed showed that the machine met the requirements of the national industry standards with a size reduced to approximately one half of the Baxter Aquarius machine. The clearance of harmful substances by the machine described here was equal to that of the Baxter Aquarius machine and was adequate for clinical purposes. Conclusions: The novel prototype performed well in all situations tested and can aid rescue work on disaster sites.</description><subject>Acute Kidney Injury - blood</subject><subject>Acute Kidney Injury - physiopathology</subject><subject>Acute Kidney Injury - therapy</subject><subject>Adult</subject><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Dogs</subject><subject>Emergency and intensive care: renal failure. Dialysis management</subject><subject>Emergency Medical Services</subject><subject>Equipment Design</subject><subject>Female</subject><subject>Hemofiltration - instrumentation</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Kidney - physiopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Original Paper</subject><subject>Renal Replacement Therapy - instrumentation</subject><issn>0253-5068</issn><issn>1421-9735</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0DtPwzAUBWALgWgpDOwIeUGCIeD4kdhjKeUhFVFV3SPXscGQ2sVOhv57jBrKdJdP5957ADjP0W2eM3GHECKkQAIfgGFOcZ6JkrBDMESYkYyhgg_ASYyfCOW0YOIYDDAmlJSCDcFiDOc-tHLVaDjxrrWu812E9433NZx3wRqrZGu9g69SfVinofEBTtc6vGuntnCho-o0tA4-2Chjq0M8BUdGNlGf9XMElo_T5eQ5m709vUzGs0ylY9uMl5JhVmCDqCA1VhiXDCOCqVGiVExpwgVDSlKOxYoWiFClmKCGEFpzLMkIXO9iN8F_dzq21dpGpZtGOp1eqHKEKS05ISLRmx1VwccYtKk2wa5l2CZU_TZY7RtM9rKP7VZrXe_lX2UJXPVARiUbE6RTNv67lMIpL5O72LkvmboKe9Dv-QG6F38L</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>He, Ping</creator><creator>Zhou, Chunhua</creator><creator>Li, Hongyan</creator><creator>Yu, Yongwu</creator><creator>Dong, Zhen</creator><creator>Wen, Yuanyuan</creator><creator>Li, Ping</creator><creator>Tang, Wenhong</creator><creator>Wang, Xue</creator><general>Karger</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120101</creationdate><title>A Portable Continuous Blood Purification Machine for Emergency Rescue in Disasters</title><author>He, Ping ; Zhou, Chunhua ; Li, Hongyan ; Yu, Yongwu ; Dong, Zhen ; Wen, Yuanyuan ; Li, Ping ; Tang, Wenhong ; Wang, Xue</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c336t-87a52562f0493d2c227520324fc97c5ce38950ca4829b46034cc594f334d82a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acute Kidney Injury - blood</topic><topic>Acute Kidney Injury - physiopathology</topic><topic>Acute Kidney Injury - therapy</topic><topic>Adult</topic><topic>Aged</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Dogs</topic><topic>Emergency and intensive care: renal failure. Dialysis management</topic><topic>Emergency Medical Services</topic><topic>Equipment Design</topic><topic>Female</topic><topic>Hemofiltration - instrumentation</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Kidney - physiopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Original Paper</topic><topic>Renal Replacement Therapy - instrumentation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>He, Ping</creatorcontrib><creatorcontrib>Zhou, Chunhua</creatorcontrib><creatorcontrib>Li, Hongyan</creatorcontrib><creatorcontrib>Yu, Yongwu</creatorcontrib><creatorcontrib>Dong, Zhen</creatorcontrib><creatorcontrib>Wen, Yuanyuan</creatorcontrib><creatorcontrib>Li, Ping</creatorcontrib><creatorcontrib>Tang, Wenhong</creatorcontrib><creatorcontrib>Wang, Xue</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Blood purification</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>He, Ping</au><au>Zhou, Chunhua</au><au>Li, Hongyan</au><au>Yu, Yongwu</au><au>Dong, Zhen</au><au>Wen, Yuanyuan</au><au>Li, Ping</au><au>Tang, Wenhong</au><au>Wang, Xue</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Portable Continuous Blood Purification Machine for Emergency Rescue in Disasters</atitle><jtitle>Blood purification</jtitle><addtitle>Blood Purif</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>33</volume><issue>4</issue><spage>227</spage><epage>237</epage><pages>227-237</pages><issn>0253-5068</issn><eissn>1421-9735</eissn><coden>BLPUDO</coden><abstract>Background: Continuous renal replacement therapy plays an important role in emergency rescue. Currently, no continuous renal replacement therapy machine can be used under unstable conditions as the fluid flow of these machines is controlled electronically. A novel machine that can provide emergency continuous renal replacement therapy in disaster rescue is therefore needed. Methods: Based on a volumetric metering method, a prototype portable continuous blood purifier based on a volumetric metering method was developed. Basic performance tests, special environmental tests, animal experiments and clinical use of the novel machine were completed to test and verify its performance under unstable conditions. Results: All tests completed showed that the machine met the requirements of the national industry standards with a size reduced to approximately one half of the Baxter Aquarius machine. The clearance of harmful substances by the machine described here was equal to that of the Baxter Aquarius machine and was adequate for clinical purposes. Conclusions: The novel prototype performed well in all situations tested and can aid rescue work on disaster sites.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>22343795</pmid><doi>10.1159/000336092</doi><tpages>11</tpages></addata></record> |
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| source | Karger Journals; MEDLINE |
| subjects | Acute Kidney Injury - blood Acute Kidney Injury - physiopathology Acute Kidney Injury - therapy Adult Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Dogs Emergency and intensive care: renal failure. Dialysis management Emergency Medical Services Equipment Design Female Hemofiltration - instrumentation Humans Intensive care medicine Kidney - physiopathology Male Medical sciences Middle Aged Original Paper Renal Replacement Therapy - instrumentation |
| title | A Portable Continuous Blood Purification Machine for Emergency Rescue in Disasters |
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