The influence of orifice height on flow rate of powder excipients
The influence of the orifice height of a cylindrical, flat-bottomed hopper on the mass flow rate of the free-flowable size fractions of sodium chloride and boric acid was investigated. It was observed that a zone of sudden acceleration of the mass flow under gravity occurred when a critical orifice...
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| Veröffentlicht in: | Pharmazie 2011-12, Vol.66 (12), p.953-955 |
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| creator | Zatloukal Šklubalová |
| description | The influence of the orifice height of a cylindrical, flat-bottomed hopper on the mass flow rate of the free-flowable size fractions of sodium chloride and boric acid was investigated. It was observed that a zone of sudden acceleration of the mass flow under gravity occurred when a
critical orifice height had been achieved. Based on the results, an orifice diameter equal to 12 mm with a height of between 8-16 mm is recommended for the faster flow of sodium chloride while an orifice diameter equal to 8 mm with a height of less than 8 mm is appropriate for the slower
flow of boric acid. In summary, the orifice height should be taken into consideration as an important parameter of a cylindrical test hopper in order to obtain a reproducible and comparable mass flow as the single-point characteristic of powder flowability. |
| doi_str_mv | 10.1691/ph.2011.1074 |
| format | Article |
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critical orifice height had been achieved. Based on the results, an orifice diameter equal to 12 mm with a height of between 8-16 mm is recommended for the faster flow of sodium chloride while an orifice diameter equal to 8 mm with a height of less than 8 mm is appropriate for the slower
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critical orifice height had been achieved. Based on the results, an orifice diameter equal to 12 mm with a height of between 8-16 mm is recommended for the faster flow of sodium chloride while an orifice diameter equal to 8 mm with a height of less than 8 mm is appropriate for the slower
flow of boric acid. In summary, the orifice height should be taken into consideration as an important parameter of a cylindrical test hopper in order to obtain a reproducible and comparable mass flow as the single-point characteristic of powder flowability.</description><subject>Boric Acids</subject><subject>Excipients</subject><subject>Humidity</subject><subject>Particle Size</subject><subject>Powders</subject><subject>Reproducibility of Results</subject><subject>Sodium Chloride</subject><subject>Technology, Pharmaceutical - standards</subject><subject>Temperature</subject><subject>Vibration</subject><issn>0031-7144</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kbtPwzAQxj2AaClszCgbU4tfcZyxKk-pEgxltpzknLhK4-AkBfrX4z4YueU-6b776R4I3RA8IyIl9201o5iQGcEJP0NjjBmZJoTzEbrsujXGVFAhL9CIUkZogskYzVcVRLYx9QBNDpEzkfPW2CArsGXVR66JTO2-Iq_7Q7l1XwX4CL5z21po-u4KnRtdd3B9yhP08fS4WrxMl2_Pr4v5cmoZ5_00pikAaC0yUxRAMcQxzpjRlCYipcawQsZcsgKKmHKRcpZJHuM4lSSVcaJzNkF3R27r3ecAXa82tsuhrnUDbuhUSnEihUxJcN6enEO2gUK13m60_1F_WwfDw9FgmzKsoNXaDb4Jw6vSba1qK-03eqf2p1T4EEKcBKFK-34vcMC8_4Ox-ZG0f8D-_morRBNaKaYES8IUCUhVgNFD3atee1XuVBeQv3uRhlM</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>Zatloukal</creator><creator>Šklubalová</creator><general>Govi-Verlag</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20111201</creationdate><title>The influence of orifice height on flow rate of powder excipients</title><author>Zatloukal ; Šklubalová</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i344t-529eeeaa6bfdde20e550b3fa227692ff3d85483ded5246943b845059819857ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Boric Acids</topic><topic>Excipients</topic><topic>Humidity</topic><topic>Particle Size</topic><topic>Powders</topic><topic>Reproducibility of Results</topic><topic>Sodium Chloride</topic><topic>Technology, Pharmaceutical - standards</topic><topic>Temperature</topic><topic>Vibration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zatloukal</creatorcontrib><creatorcontrib>Šklubalová</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmazie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zatloukal</au><au>Šklubalová</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The influence of orifice height on flow rate of powder excipients</atitle><jtitle>Pharmazie</jtitle><stitle>Pharmazie</stitle><addtitle>Pharmazie</addtitle><date>2011-12-01</date><risdate>2011</risdate><volume>66</volume><issue>12</issue><spage>953</spage><epage>955</epage><pages>953-955</pages><issn>0031-7144</issn><abstract>The influence of the orifice height of a cylindrical, flat-bottomed hopper on the mass flow rate of the free-flowable size fractions of sodium chloride and boric acid was investigated. It was observed that a zone of sudden acceleration of the mass flow under gravity occurred when a
critical orifice height had been achieved. Based on the results, an orifice diameter equal to 12 mm with a height of between 8-16 mm is recommended for the faster flow of sodium chloride while an orifice diameter equal to 8 mm with a height of less than 8 mm is appropriate for the slower
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| fulltext | fulltext |
| identifier | ISSN: 0031-7144 |
| ispartof | Pharmazie, 2011-12, Vol.66 (12), p.953-955 |
| issn | 0031-7144 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; IngentaConnect Free/Open Access Journals |
| subjects | Boric Acids Excipients Humidity Particle Size Powders Reproducibility of Results Sodium Chloride Technology, Pharmaceutical - standards Temperature Vibration |
| title | The influence of orifice height on flow rate of powder excipients |
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